| Full name: apolipoprotein L6 | Alias Symbol: APOL-VI|APOLVI | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 80830 | HGNC ID: HGNC:14870 | Ensembl Gene: ENSG00000221963 | OMIM ID: 607256 |
Expression of APOL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOL6 | 80830 | 1557116_at | -0.0691 | 0.9409 | |
| GSE20347 | APOL6 | 80830 | 219716_at | -0.1244 | 0.6508 | |
| GSE23400 | APOL6 | 80830 | 219716_at | -0.0011 | 0.9884 | |
| GSE26886 | APOL6 | 80830 | 219716_at | -0.6570 | 0.0468 | |
| GSE29001 | APOL6 | 80830 | 219716_at | 0.0186 | 0.9461 | |
| GSE38129 | APOL6 | 80830 | 219716_at | -0.1376 | 0.4984 | |
| GSE45670 | APOL6 | 80830 | 1557116_at | 0.3383 | 0.2662 | |
| GSE53622 | APOL6 | 80830 | 170865 | -0.0024 | 0.9887 | |
| GSE53624 | APOL6 | 80830 | 40766 | 0.1237 | 0.3138 | |
| GSE63941 | APOL6 | 80830 | 219716_at | -0.3286 | 0.7566 | |
| GSE77861 | APOL6 | 80830 | 241869_at | 0.1677 | 0.6065 | |
| GSE97050 | APOL6 | 80830 | A_23_P155052 | 0.4559 | 0.4985 | |
| SRP007169 | APOL6 | 80830 | RNAseq | 0.1248 | 0.7923 | |
| SRP008496 | APOL6 | 80830 | RNAseq | -0.3161 | 0.3558 | |
| SRP064894 | APOL6 | 80830 | RNAseq | 0.6498 | 0.0043 | |
| SRP133303 | APOL6 | 80830 | RNAseq | 0.3164 | 0.1112 | |
| SRP159526 | APOL6 | 80830 | RNAseq | -0.4197 | 0.3385 | |
| SRP193095 | APOL6 | 80830 | RNAseq | 0.0590 | 0.6878 | |
| SRP219564 | APOL6 | 80830 | RNAseq | 1.2620 | 0.0433 | |
| TCGA | APOL6 | 80830 | RNAseq | 0.0730 | 0.3541 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by APOL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOL6 | 80830 | 4 | 6 | 20 | |
| GSE20123 | APOL6 | 80830 | 4 | 5 | 21 | |
| GSE43470 | APOL6 | 80830 | 4 | 7 | 32 | |
| GSE46452 | APOL6 | 80830 | 31 | 1 | 27 | |
| GSE47630 | APOL6 | 80830 | 8 | 5 | 27 | |
| GSE54993 | APOL6 | 80830 | 3 | 6 | 61 | |
| GSE54994 | APOL6 | 80830 | 9 | 9 | 35 | |
| GSE60625 | APOL6 | 80830 | 5 | 0 | 6 | |
| GSE74703 | APOL6 | 80830 | 4 | 5 | 27 | |
| GSE74704 | APOL6 | 80830 | 1 | 2 | 17 | |
| TCGA | APOL6 | 80830 | 27 | 15 | 54 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of APOL6:
Generating mutation plots.
Highly correlated genes for APOL6:
Showing top 20/186 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOL6 | TAGAP | 0.714951 | 3 | 0 | 3 |
| APOL6 | GBP4 | 0.713428 | 6 | 0 | 5 |
| APOL6 | DOCK10 | 0.711569 | 3 | 0 | 3 |
| APOL6 | RNF213 | 0.709091 | 5 | 0 | 5 |
| APOL6 | UBA6 | 0.697418 | 3 | 0 | 3 |
| APOL6 | FAM107B | 0.687853 | 3 | 0 | 3 |
| APOL6 | E2F8 | 0.681504 | 3 | 0 | 3 |
| APOL6 | HCLS1 | 0.671469 | 4 | 0 | 3 |
| APOL6 | VPS53 | 0.671317 | 3 | 0 | 3 |
| APOL6 | PARP9 | 0.668682 | 7 | 0 | 6 |
| APOL6 | DDX60L | 0.666138 | 4 | 0 | 3 |
| APOL6 | EPSTI1 | 0.666087 | 5 | 0 | 4 |
| APOL6 | SAMD9L | 0.664475 | 6 | 0 | 6 |
| APOL6 | IFITM3 | 0.659931 | 3 | 0 | 3 |
| APOL6 | UBASH3A | 0.655567 | 4 | 0 | 3 |
| APOL6 | IL15 | 0.653872 | 5 | 0 | 5 |
| APOL6 | TAOK3 | 0.651352 | 3 | 0 | 3 |
| APOL6 | RTP4 | 0.650471 | 7 | 0 | 6 |
| APOL6 | APOL3 | 0.649935 | 8 | 0 | 6 |
| APOL6 | PIK3R5 | 0.647016 | 3 | 0 | 3 |
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