| Full name: aquaporin 3 (Gill blood group) | Alias Symbol: GIL | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 360 | HGNC ID: HGNC:636 | Ensembl Gene: ENSG00000165272 | OMIM ID: 600170 |
| Drug and gene relationship at DGIdb | |||
Expression of AQP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQP3 | 360 | 39248_at | -0.9848 | 0.4881 | |
| GSE20347 | AQP3 | 360 | 39248_at | -2.0137 | 0.0001 | |
| GSE23400 | AQP3 | 360 | 39248_at | -1.8420 | 0.0000 | |
| GSE26886 | AQP3 | 360 | 39248_at | -2.0780 | 0.0004 | |
| GSE29001 | AQP3 | 360 | 39248_at | -1.0092 | 0.0192 | |
| GSE38129 | AQP3 | 360 | 39248_at | -1.3387 | 0.0415 | |
| GSE45670 | AQP3 | 360 | 39248_at | -0.2159 | 0.5164 | |
| GSE53622 | AQP3 | 360 | 67778 | -2.2027 | 0.0000 | |
| GSE53624 | AQP3 | 360 | 67778 | -2.7202 | 0.0000 | |
| GSE63941 | AQP3 | 360 | 39248_at | 2.5848 | 0.1631 | |
| GSE77861 | AQP3 | 360 | 39248_at | -2.3129 | 0.0473 | |
| GSE97050 | AQP3 | 360 | A_33_P3209591 | -0.2572 | 0.8875 | |
| SRP007169 | AQP3 | 360 | RNAseq | -6.4051 | 0.0000 | |
| SRP008496 | AQP3 | 360 | RNAseq | -6.0812 | 0.0000 | |
| SRP064894 | AQP3 | 360 | RNAseq | -2.8110 | 0.0000 | |
| SRP133303 | AQP3 | 360 | RNAseq | -3.0897 | 0.0000 | |
| SRP159526 | AQP3 | 360 | RNAseq | -4.5656 | 0.0000 | |
| SRP193095 | AQP3 | 360 | RNAseq | -2.9183 | 0.0000 | |
| SRP219564 | AQP3 | 360 | RNAseq | -2.2579 | 0.0422 | |
| TCGA | AQP3 | 360 | RNAseq | 0.3139 | 0.0965 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by AQP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQP3 | 360 | 3 | 13 | 14 | |
| GSE20123 | AQP3 | 360 | 3 | 13 | 14 | |
| GSE43470 | AQP3 | 360 | 3 | 10 | 30 | |
| GSE46452 | AQP3 | 360 | 7 | 15 | 37 | |
| GSE47630 | AQP3 | 360 | 1 | 21 | 18 | |
| GSE54993 | AQP3 | 360 | 6 | 0 | 64 | |
| GSE54994 | AQP3 | 360 | 7 | 11 | 35 | |
| GSE60625 | AQP3 | 360 | 0 | 0 | 11 | |
| GSE74703 | AQP3 | 360 | 2 | 7 | 27 | |
| GSE74704 | AQP3 | 360 | 0 | 10 | 10 | |
| TCGA | AQP3 | 360 | 16 | 44 | 36 |
Total number of gains: 48; Total number of losses: 144; Total Number of normals: 296.
Somatic mutations of AQP3:
Generating mutation plots.
Highly correlated genes for AQP3:
Showing top 20/1047 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQP3 | C3orf20 | 0.773008 | 3 | 0 | 3 |
| AQP3 | SPRR2E | 0.761839 | 3 | 0 | 3 |
| AQP3 | S100A9 | 0.761831 | 11 | 0 | 10 |
| AQP3 | S100A8 | 0.761005 | 11 | 0 | 10 |
| AQP3 | APOBEC1 | 0.757161 | 3 | 0 | 3 |
| AQP3 | CYSRT1 | 0.753522 | 6 | 0 | 5 |
| AQP3 | KLK13 | 0.749414 | 12 | 0 | 11 |
| AQP3 | SPRR3 | 0.748972 | 10 | 0 | 10 |
| AQP3 | KRT13 | 0.745854 | 11 | 0 | 10 |
| AQP3 | IL1RN | 0.742907 | 13 | 0 | 11 |
| AQP3 | EHF | 0.735642 | 12 | 0 | 12 |
| AQP3 | HOPX | 0.732614 | 11 | 0 | 10 |
| AQP3 | CSTB | 0.732168 | 12 | 0 | 10 |
| AQP3 | SPRR1A | 0.731229 | 11 | 0 | 10 |
| AQP3 | S100A14 | 0.726962 | 13 | 0 | 12 |
| AQP3 | SERPINB13 | 0.725896 | 11 | 0 | 10 |
| AQP3 | TGM3 | 0.723189 | 10 | 0 | 10 |
| AQP3 | LY6D | 0.723067 | 13 | 0 | 13 |
| AQP3 | SPINK5 | 0.722339 | 12 | 0 | 10 |
| AQP3 | UPK3B | 0.72042 | 3 | 0 | 3 |
For details and further investigation, click here
