| Full name: asporin | Alias Symbol: FLJ20129|SLRR1C|PLAP-1 | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 54829 | HGNC ID: HGNC:14872 | Ensembl Gene: ENSG00000106819 | OMIM ID: 608135 |
| Drug and gene relationship at DGIdb | |||
Expression of ASPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPN | 54829 | 219087_at | 0.6891 | 0.4957 | |
| GSE20347 | ASPN | 54829 | 219087_at | 1.7397 | 0.0029 | |
| GSE23400 | ASPN | 54829 | 219087_at | 1.6469 | 0.0000 | |
| GSE26886 | ASPN | 54829 | 219087_at | 2.0587 | 0.0044 | |
| GSE29001 | ASPN | 54829 | 219087_at | 1.7477 | 0.0009 | |
| GSE38129 | ASPN | 54829 | 219087_at | 1.5325 | 0.0019 | |
| GSE45670 | ASPN | 54829 | 219087_at | 0.0142 | 0.9854 | |
| GSE53622 | ASPN | 54829 | 107275 | 1.8081 | 0.0000 | |
| GSE53624 | ASPN | 54829 | 107275 | 1.6219 | 0.0000 | |
| GSE63941 | ASPN | 54829 | 219087_at | -3.6015 | 0.0001 | |
| GSE77861 | ASPN | 54829 | 219087_at | 1.2938 | 0.0495 | |
| GSE97050 | ASPN | 54829 | A_33_P3216059 | 0.3730 | 0.2858 | |
| SRP007169 | ASPN | 54829 | RNAseq | 5.4145 | 0.0000 | |
| SRP008496 | ASPN | 54829 | RNAseq | 5.4950 | 0.0000 | |
| SRP064894 | ASPN | 54829 | RNAseq | 2.6445 | 0.0000 | |
| SRP133303 | ASPN | 54829 | RNAseq | 2.4668 | 0.0000 | |
| SRP159526 | ASPN | 54829 | RNAseq | 1.5283 | 0.0019 | |
| SRP193095 | ASPN | 54829 | RNAseq | 1.6881 | 0.0000 | |
| SRP219564 | ASPN | 54829 | RNAseq | 0.6470 | 0.4584 | |
| TCGA | ASPN | 54829 | RNAseq | 0.3636 | 0.0449 |
Upregulated datasets: 14; Downregulated datasets: 1.
Survival by ASPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPN | 54829 | 6 | 9 | 15 | |
| GSE20123 | ASPN | 54829 | 6 | 9 | 15 | |
| GSE43470 | ASPN | 54829 | 6 | 3 | 34 | |
| GSE46452 | ASPN | 54829 | 6 | 14 | 39 | |
| GSE47630 | ASPN | 54829 | 1 | 17 | 22 | |
| GSE54993 | ASPN | 54829 | 4 | 2 | 64 | |
| GSE54994 | ASPN | 54829 | 8 | 11 | 34 | |
| GSE60625 | ASPN | 54829 | 0 | 0 | 11 | |
| GSE74703 | ASPN | 54829 | 5 | 3 | 28 | |
| GSE74704 | ASPN | 54829 | 3 | 7 | 10 | |
| TCGA | ASPN | 54829 | 24 | 24 | 48 |
Total number of gains: 69; Total number of losses: 99; Total Number of normals: 320.
Somatic mutations of ASPN:
Generating mutation plots.
Highly correlated genes for ASPN:
Showing top 20/681 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPN | COL3A1 | 0.771011 | 11 | 0 | 11 |
| ASPN | POSTN | 0.757521 | 11 | 0 | 11 |
| ASPN | VCAN | 0.754659 | 12 | 0 | 12 |
| ASPN | SPARC | 0.749742 | 12 | 0 | 12 |
| ASPN | COL6A3 | 0.747717 | 12 | 0 | 11 |
| ASPN | SFRP4 | 0.745614 | 11 | 0 | 10 |
| ASPN | NID2 | 0.733782 | 9 | 0 | 9 |
| ASPN | ISLR | 0.731842 | 12 | 0 | 11 |
| ASPN | COL1A2 | 0.731282 | 12 | 0 | 10 |
| ASPN | COL8A1 | 0.728708 | 9 | 0 | 9 |
| ASPN | FNDC1 | 0.728151 | 8 | 0 | 8 |
| ASPN | CTSK | 0.724506 | 12 | 0 | 11 |
| ASPN | COL5A1 | 0.724202 | 12 | 0 | 11 |
| ASPN | MXRA8 | 0.723217 | 11 | 0 | 11 |
| ASPN | FN1 | 0.719847 | 12 | 0 | 12 |
| ASPN | LUM | 0.719143 | 12 | 0 | 11 |
| ASPN | COL5A2 | 0.713794 | 12 | 0 | 10 |
| ASPN | AEBP1 | 0.705648 | 12 | 0 | 12 |
| ASPN | COL6A2 | 0.704888 | 11 | 0 | 11 |
| ASPN | CDH11 | 0.700552 | 12 | 0 | 10 |
For details and further investigation, click here
