| Full name: BMP and activin membrane bound inhibitor | Alias Symbol: NMA | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 25805 | HGNC ID: HGNC:30251 | Ensembl Gene: ENSG00000095739 | OMIM ID: 604444 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
BAMBI involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04310 | Wnt signaling pathway | |
| hsa04350 | TGF-beta signaling pathway |
Expression of BAMBI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAMBI | 25805 | 203304_at | 1.0194 | 0.1557 | |
| GSE20347 | BAMBI | 25805 | 203304_at | 1.4590 | 0.0033 | |
| GSE23400 | BAMBI | 25805 | 203304_at | 0.7179 | 0.0000 | |
| GSE26886 | BAMBI | 25805 | 203304_at | 2.1444 | 0.0000 | |
| GSE29001 | BAMBI | 25805 | 203304_at | 1.4499 | 0.0158 | |
| GSE38129 | BAMBI | 25805 | 203304_at | 1.8457 | 0.0000 | |
| GSE45670 | BAMBI | 25805 | 203304_at | 1.3750 | 0.0107 | |
| GSE53622 | BAMBI | 25805 | 77977 | 1.7260 | 0.0000 | |
| GSE53624 | BAMBI | 25805 | 77977 | 2.2179 | 0.0000 | |
| GSE63941 | BAMBI | 25805 | 203304_at | -1.5874 | 0.3948 | |
| GSE77861 | BAMBI | 25805 | 203304_at | 2.1016 | 0.0045 | |
| GSE97050 | BAMBI | 25805 | A_23_P52207 | 0.0261 | 0.9728 | |
| SRP007169 | BAMBI | 25805 | RNAseq | 2.2233 | 0.0083 | |
| SRP064894 | BAMBI | 25805 | RNAseq | 1.6719 | 0.0001 | |
| SRP133303 | BAMBI | 25805 | RNAseq | 2.0877 | 0.0000 | |
| SRP159526 | BAMBI | 25805 | RNAseq | 3.2593 | 0.0000 | |
| SRP219564 | BAMBI | 25805 | RNAseq | 1.6934 | 0.0442 | |
| TCGA | BAMBI | 25805 | RNAseq | 0.8041 | 0.0001 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by BAMBI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAMBI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAMBI | 25805 | 5 | 7 | 18 | |
| GSE20123 | BAMBI | 25805 | 5 | 6 | 19 | |
| GSE43470 | BAMBI | 25805 | 3 | 4 | 36 | |
| GSE46452 | BAMBI | 25805 | 1 | 14 | 44 | |
| GSE47630 | BAMBI | 25805 | 5 | 15 | 20 | |
| GSE54993 | BAMBI | 25805 | 9 | 0 | 61 | |
| GSE54994 | BAMBI | 25805 | 3 | 9 | 41 | |
| GSE60625 | BAMBI | 25805 | 0 | 0 | 11 | |
| GSE74703 | BAMBI | 25805 | 2 | 2 | 32 | |
| GSE74704 | BAMBI | 25805 | 0 | 5 | 15 | |
| TCGA | BAMBI | 25805 | 19 | 23 | 54 |
Total number of gains: 52; Total number of losses: 85; Total Number of normals: 351.
Somatic mutations of BAMBI:
Generating mutation plots.
Highly correlated genes for BAMBI:
Showing top 20/926 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAMBI | HOXC9 | 0.688102 | 4 | 0 | 4 |
| BAMBI | WDR54 | 0.683543 | 6 | 0 | 6 |
| BAMBI | GALNT18 | 0.680966 | 6 | 0 | 5 |
| BAMBI | PXDN | 0.675221 | 10 | 0 | 9 |
| BAMBI | YIF1A | 0.675178 | 5 | 0 | 5 |
| BAMBI | KNSTRN | 0.671041 | 6 | 0 | 6 |
| BAMBI | SIX4 | 0.670855 | 7 | 0 | 6 |
| BAMBI | PRTFDC1 | 0.665634 | 5 | 0 | 4 |
| BAMBI | HEY1 | 0.665263 | 11 | 0 | 10 |
| BAMBI | SHISA2 | 0.661841 | 6 | 0 | 6 |
| BAMBI | TOP1MT | 0.657842 | 5 | 0 | 4 |
| BAMBI | NAT14 | 0.657792 | 5 | 0 | 5 |
| BAMBI | RFC4 | 0.657762 | 10 | 0 | 10 |
| BAMBI | SGCE | 0.657756 | 4 | 0 | 3 |
| BAMBI | PSMG3 | 0.657488 | 5 | 0 | 5 |
| BAMBI | RNF175 | 0.655417 | 4 | 0 | 3 |
| BAMBI | KCNK1 | 0.655127 | 3 | 0 | 3 |
| BAMBI | KCNS3 | 0.654327 | 11 | 0 | 10 |
| BAMBI | SPRR2G | 0.653885 | 3 | 0 | 3 |
| BAMBI | IRF2BPL | 0.653599 | 5 | 0 | 4 |
For details and further investigation, click here
