| Full name: cadherin 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q21 | ||
| Entrez ID: 1006 | HGNC ID: HGNC:1767 | Ensembl Gene: ENSG00000150394 | OMIM ID: 603008 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH8 | 1006 | 210518_at | -0.1115 | 0.6962 | |
| GSE20347 | CDH8 | 1006 | 210518_at | 0.0917 | 0.1720 | |
| GSE23400 | CDH8 | 1006 | 210518_at | -0.0084 | 0.8169 | |
| GSE26886 | CDH8 | 1006 | 210518_at | 0.1171 | 0.5987 | |
| GSE29001 | CDH8 | 1006 | 210518_at | 0.1577 | 0.2579 | |
| GSE38129 | CDH8 | 1006 | 210518_at | 0.0597 | 0.3638 | |
| GSE45670 | CDH8 | 1006 | 210518_at | 0.3100 | 0.0093 | |
| GSE53622 | CDH8 | 1006 | 2593 | 1.1480 | 0.0000 | |
| GSE53624 | CDH8 | 1006 | 2593 | 1.7215 | 0.0000 | |
| GSE63941 | CDH8 | 1006 | 210518_at | 0.2424 | 0.3918 | |
| GSE77861 | CDH8 | 1006 | 210518_at | -0.0440 | 0.6813 | |
| SRP007169 | CDH8 | 1006 | RNAseq | 2.3792 | 0.0061 | |
| SRP133303 | CDH8 | 1006 | RNAseq | 1.1573 | 0.0001 | |
| SRP159526 | CDH8 | 1006 | RNAseq | 3.1837 | 0.0000 | |
| SRP219564 | CDH8 | 1006 | RNAseq | 0.8659 | 0.2550 | |
| TCGA | CDH8 | 1006 | RNAseq | 0.9528 | 0.0332 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CDH8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH8 | 1006 | 4 | 1 | 25 | |
| GSE20123 | CDH8 | 1006 | 4 | 1 | 25 | |
| GSE43470 | CDH8 | 1006 | 2 | 7 | 34 | |
| GSE46452 | CDH8 | 1006 | 38 | 1 | 20 | |
| GSE47630 | CDH8 | 1006 | 10 | 8 | 22 | |
| GSE54993 | CDH8 | 1006 | 2 | 4 | 64 | |
| GSE54994 | CDH8 | 1006 | 6 | 10 | 37 | |
| GSE60625 | CDH8 | 1006 | 4 | 0 | 7 | |
| GSE74703 | CDH8 | 1006 | 2 | 5 | 29 | |
| GSE74704 | CDH8 | 1006 | 3 | 1 | 16 | |
| TCGA | CDH8 | 1006 | 27 | 11 | 58 |
Total number of gains: 102; Total number of losses: 49; Total Number of normals: 337.
Somatic mutations of CDH8:
Generating mutation plots.
Highly correlated genes for CDH8:
Showing top 20/41 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH8 | SAG | 0.652147 | 4 | 0 | 4 |
| CDH8 | SLC5A12 | 0.630139 | 3 | 0 | 3 |
| CDH8 | MAPK4 | 0.626518 | 3 | 0 | 3 |
| CDH8 | CHRNG | 0.601801 | 3 | 0 | 3 |
| CDH8 | RECK | 0.599632 | 4 | 0 | 3 |
| CDH8 | AMBN | 0.58874 | 3 | 0 | 3 |
| CDH8 | PRAMEF12 | 0.583603 | 5 | 0 | 3 |
| CDH8 | IL9R | 0.580297 | 4 | 0 | 3 |
| CDH8 | CLDN16 | 0.577127 | 6 | 0 | 5 |
| CDH8 | CELA3A | 0.575744 | 4 | 0 | 3 |
| CDH8 | WNT6 | 0.57076 | 5 | 0 | 3 |
| CDH8 | CALCR | 0.570011 | 5 | 0 | 4 |
| CDH8 | LINC00240 | 0.569569 | 4 | 0 | 3 |
| CDH8 | TBC1D30 | 0.555556 | 4 | 0 | 3 |
| CDH8 | COLEC10 | 0.554751 | 5 | 0 | 4 |
| CDH8 | ARHGAP24 | 0.553702 | 4 | 0 | 3 |
| CDH8 | ANO3 | 0.553687 | 5 | 0 | 3 |
| CDH8 | PRMT8 | 0.545875 | 4 | 0 | 3 |
| CDH8 | LINGO2 | 0.544122 | 4 | 0 | 3 |
| CDH8 | KCNJ14 | 0.54353 | 5 | 0 | 3 |
For details and further investigation, click here
