| Full name: casein alpha s1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 1446 | HGNC ID: HGNC:2445 | Ensembl Gene: ENSG00000126545 | OMIM ID: 115450 |
| Drug and gene relationship at DGIdb | |||
Expression of CSN1S1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSN1S1 | 1446 | 208350_at | 0.0793 | 0.7732 | |
| GSE20347 | CSN1S1 | 1446 | 208350_at | -0.0495 | 0.5216 | |
| GSE23400 | CSN1S1 | 1446 | 208350_at | -0.0468 | 0.8238 | |
| GSE26886 | CSN1S1 | 1446 | 208350_at | -0.0285 | 0.7740 | |
| GSE29001 | CSN1S1 | 1446 | 208350_at | -0.0518 | 0.7224 | |
| GSE38129 | CSN1S1 | 1446 | 208350_at | -0.1057 | 0.0516 | |
| GSE45670 | CSN1S1 | 1446 | 208350_at | -0.1359 | 0.1634 | |
| GSE53622 | CSN1S1 | 1446 | 10708 | -0.0540 | 0.8367 | |
| GSE53624 | CSN1S1 | 1446 | 10708 | -0.2326 | 0.0296 | |
| GSE63941 | CSN1S1 | 1446 | 208350_at | 0.0424 | 0.7982 | |
| GSE77861 | CSN1S1 | 1446 | 208350_at | -0.1148 | 0.0846 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CSN1S1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSN1S1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSN1S1 | 1446 | 0 | 10 | 20 | |
| GSE20123 | CSN1S1 | 1446 | 0 | 11 | 19 | |
| GSE43470 | CSN1S1 | 1446 | 0 | 13 | 30 | |
| GSE46452 | CSN1S1 | 1446 | 2 | 35 | 22 | |
| GSE47630 | CSN1S1 | 1446 | 1 | 18 | 21 | |
| GSE54993 | CSN1S1 | 1446 | 7 | 0 | 63 | |
| GSE54994 | CSN1S1 | 1446 | 1 | 9 | 43 | |
| GSE60625 | CSN1S1 | 1446 | 0 | 0 | 11 | |
| GSE74703 | CSN1S1 | 1446 | 0 | 11 | 25 | |
| GSE74704 | CSN1S1 | 1446 | 0 | 7 | 13 | |
| TCGA | CSN1S1 | 1446 | 15 | 28 | 53 |
Total number of gains: 26; Total number of losses: 142; Total Number of normals: 320.
Somatic mutations of CSN1S1:
Generating mutation plots.
Highly correlated genes for CSN1S1:
Showing top 20/349 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSN1S1 | CIITA | 0.699888 | 3 | 0 | 3 |
| CSN1S1 | ITK | 0.683537 | 4 | 0 | 3 |
| CSN1S1 | PIK3R5 | 0.678327 | 4 | 0 | 4 |
| CSN1S1 | MTAP | 0.676016 | 3 | 0 | 3 |
| CSN1S1 | CSF2 | 0.671885 | 3 | 0 | 3 |
| CSN1S1 | GML | 0.669846 | 3 | 0 | 3 |
| CSN1S1 | SCN11A | 0.662055 | 3 | 0 | 3 |
| CSN1S1 | GAD2 | 0.655351 | 3 | 0 | 3 |
| CSN1S1 | WAS | 0.653873 | 3 | 0 | 3 |
| CSN1S1 | POU4F2 | 0.653696 | 3 | 0 | 3 |
| CSN1S1 | GK2 | 0.652962 | 3 | 0 | 3 |
| CSN1S1 | GABRB2 | 0.652302 | 4 | 0 | 3 |
| CSN1S1 | IL21 | 0.651833 | 3 | 0 | 3 |
| CSN1S1 | DAB1 | 0.651446 | 4 | 0 | 4 |
| CSN1S1 | TAAR5 | 0.648331 | 6 | 0 | 6 |
| CSN1S1 | ESR2 | 0.648061 | 3 | 0 | 3 |
| CSN1S1 | HAAO | 0.640432 | 5 | 0 | 5 |
| CSN1S1 | KSR1 | 0.638635 | 4 | 0 | 3 |
| CSN1S1 | OR6A2 | 0.63858 | 5 | 0 | 4 |
| CSN1S1 | KIR2DS3 | 0.63293 | 3 | 0 | 3 |
For details and further investigation, click here
