| Full name: dynactin subunit 5 | Alias Symbol: MGC3248|p25 | ||
| Type: protein-coding gene | Cytoband: 16p12.2 | ||
| Entrez ID: 84516 | HGNC ID: HGNC:24594 | Ensembl Gene: ENSG00000166847 | OMIM ID: 612962 |
Screen Evidence:
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Expression of DCTN5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCTN5 | 84516 | 209232_s_at | 0.0493 | 0.9516 | |
| GSE20347 | DCTN5 | 84516 | 209232_s_at | -0.0611 | 0.5515 | |
| GSE23400 | DCTN5 | 84516 | 209232_s_at | 0.1521 | 0.0010 | |
| GSE26886 | DCTN5 | 84516 | 209232_s_at | -0.8802 | 0.0000 | |
| GSE29001 | DCTN5 | 84516 | 209232_s_at | 0.1495 | 0.4416 | |
| GSE38129 | DCTN5 | 84516 | 209232_s_at | 0.1002 | 0.3508 | |
| GSE45670 | DCTN5 | 84516 | 1556646_at | 0.1693 | 0.2077 | |
| GSE53622 | DCTN5 | 84516 | 29739 | 0.0211 | 0.7496 | |
| GSE53624 | DCTN5 | 84516 | 29739 | -0.0011 | 0.9914 | |
| GSE63941 | DCTN5 | 84516 | 209231_s_at | 1.1686 | 0.0043 | |
| GSE77861 | DCTN5 | 84516 | 209232_s_at | 0.0207 | 0.9219 | |
| GSE97050 | DCTN5 | 84516 | A_23_P309967 | 0.1136 | 0.6049 | |
| SRP007169 | DCTN5 | 84516 | RNAseq | -0.9438 | 0.0641 | |
| SRP008496 | DCTN5 | 84516 | RNAseq | -0.4250 | 0.2302 | |
| SRP064894 | DCTN5 | 84516 | RNAseq | -0.2011 | 0.1379 | |
| SRP133303 | DCTN5 | 84516 | RNAseq | 0.1462 | 0.3906 | |
| SRP159526 | DCTN5 | 84516 | RNAseq | -0.1432 | 0.5325 | |
| SRP193095 | DCTN5 | 84516 | RNAseq | -0.3013 | 0.0013 | |
| SRP219564 | DCTN5 | 84516 | RNAseq | -0.4218 | 0.1176 | |
| TCGA | DCTN5 | 84516 | RNAseq | 0.0271 | 0.5579 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DCTN5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCTN5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCTN5 | 84516 | 6 | 4 | 20 | |
| GSE20123 | DCTN5 | 84516 | 6 | 3 | 21 | |
| GSE43470 | DCTN5 | 84516 | 3 | 3 | 37 | |
| GSE46452 | DCTN5 | 84516 | 38 | 1 | 20 | |
| GSE47630 | DCTN5 | 84516 | 11 | 6 | 23 | |
| GSE54993 | DCTN5 | 84516 | 3 | 5 | 62 | |
| GSE54994 | DCTN5 | 84516 | 4 | 8 | 41 | |
| GSE60625 | DCTN5 | 84516 | 4 | 0 | 7 | |
| GSE74703 | DCTN5 | 84516 | 3 | 2 | 31 | |
| GSE74704 | DCTN5 | 84516 | 3 | 1 | 16 | |
| TCGA | DCTN5 | 84516 | 19 | 14 | 63 |
Total number of gains: 100; Total number of losses: 47; Total Number of normals: 341.
Somatic mutations of DCTN5:
Generating mutation plots.
Highly correlated genes for DCTN5:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCTN5 | TM7SF2 | 0.683429 | 3 | 0 | 3 |
| DCTN5 | DUOX2 | 0.661592 | 3 | 0 | 3 |
| DCTN5 | LEO1 | 0.658972 | 3 | 0 | 3 |
| DCTN5 | MARS2 | 0.657587 | 3 | 0 | 3 |
| DCTN5 | PEX2 | 0.652953 | 4 | 0 | 3 |
| DCTN5 | RNF8 | 0.652743 | 3 | 0 | 3 |
| DCTN5 | ASL | 0.651272 | 3 | 0 | 3 |
| DCTN5 | TMEM33 | 0.649531 | 4 | 0 | 3 |
| DCTN5 | ZW10 | 0.637187 | 4 | 0 | 3 |
| DCTN5 | FGGY | 0.635892 | 4 | 0 | 3 |
| DCTN5 | POLR2E | 0.635402 | 3 | 0 | 3 |
| DCTN5 | EIF4A3 | 0.631968 | 4 | 0 | 4 |
| DCTN5 | AGFG1 | 0.631819 | 4 | 0 | 4 |
| DCTN5 | ARL8B | 0.627814 | 4 | 0 | 4 |
| DCTN5 | PARN | 0.626217 | 7 | 0 | 5 |
| DCTN5 | CHMP4C | 0.625043 | 3 | 0 | 3 |
| DCTN5 | PRPF38A | 0.624855 | 4 | 0 | 3 |
| DCTN5 | ZNF217 | 0.622289 | 4 | 0 | 3 |
| DCTN5 | JAG1 | 0.621045 | 4 | 0 | 3 |
| DCTN5 | SDC4 | 0.619715 | 4 | 0 | 3 |
For details and further investigation, click here
