| Full name: dynein axonemal heavy chain 17 | Alias Symbol: DNEL2|FLJ40457 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 8632 | HGNC ID: HGNC:2946 | Ensembl Gene: ENSG00000187775 | OMIM ID: 610063 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH17 | 8632 | 214229_at | 2.1120 | 0.1044 | |
| GSE20347 | DNAH17 | 8632 | 214229_at | 0.9058 | 0.0005 | |
| GSE23400 | DNAH17 | 8632 | 214229_at | 0.3142 | 0.0028 | |
| GSE26886 | DNAH17 | 8632 | 214229_at | 1.5044 | 0.0000 | |
| GSE29001 | DNAH17 | 8632 | 214229_at | 1.6277 | 0.0000 | |
| GSE38129 | DNAH17 | 8632 | 214229_at | 0.8831 | 0.0003 | |
| GSE45670 | DNAH17 | 8632 | 214229_at | 1.2107 | 0.0149 | |
| GSE53622 | DNAH17 | 8632 | 33881 | 2.2086 | 0.0000 | |
| GSE53624 | DNAH17 | 8632 | 33881 | 2.8506 | 0.0000 | |
| GSE63941 | DNAH17 | 8632 | 214229_at | 0.0616 | 0.7959 | |
| GSE77861 | DNAH17 | 8632 | 214229_at | 0.2548 | 0.3929 | |
| GSE97050 | DNAH17 | A_21_P0011610 | 1.5898 | 0.2485 | ||
| SRP064894 | DNAH17 | 8632 | RNAseq | 3.4582 | 0.0000 | |
| SRP133303 | DNAH17 | 8632 | RNAseq | 3.9560 | 0.0000 | |
| SRP193095 | DNAH17 | 8632 | RNAseq | 3.9199 | 0.0000 | |
| SRP219564 | DNAH17 | 8632 | RNAseq | 1.8914 | 0.0117 | |
| TCGA | DNAH17 | 8632 | RNAseq | 1.1340 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by DNAH17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH17 | 8632 | 5 | 4 | 21 | |
| GSE20123 | DNAH17 | 8632 | 5 | 4 | 21 | |
| GSE43470 | DNAH17 | 8632 | 3 | 4 | 36 | |
| GSE46452 | DNAH17 | 8632 | 33 | 0 | 26 | |
| GSE47630 | DNAH17 | 8632 | 8 | 1 | 31 | |
| GSE54993 | DNAH17 | 8632 | 2 | 5 | 63 | |
| GSE54994 | DNAH17 | 8632 | 10 | 4 | 39 | |
| GSE60625 | DNAH17 | 8632 | 6 | 0 | 5 | |
| GSE74703 | DNAH17 | 8632 | 3 | 2 | 31 | |
| GSE74704 | DNAH17 | 8632 | 4 | 4 | 12 | |
| TCGA | DNAH17 | 8632 | 30 | 9 | 57 |
Total number of gains: 109; Total number of losses: 37; Total Number of normals: 342.
Somatic mutations of DNAH17:
Generating mutation plots.
Highly correlated genes for DNAH17:
Showing top 20/1230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH17 | RAC3 | 0.735967 | 3 | 0 | 3 |
| DNAH17 | TTYH3 | 0.705027 | 6 | 0 | 6 |
| DNAH17 | FADS3 | 0.681235 | 6 | 0 | 6 |
| DNAH17 | CCL7 | 0.679843 | 3 | 0 | 3 |
| DNAH17 | CENPW | 0.679406 | 5 | 0 | 5 |
| DNAH17 | RGS1 | 0.678229 | 3 | 0 | 3 |
| DNAH17 | MFAP2 | 0.675524 | 10 | 0 | 8 |
| DNAH17 | MRPS28 | 0.673534 | 4 | 0 | 4 |
| DNAH17 | LPCAT1 | 0.673374 | 8 | 0 | 7 |
| DNAH17 | CISD2 | 0.67096 | 3 | 0 | 3 |
| DNAH17 | LOXL2 | 0.669636 | 8 | 0 | 7 |
| DNAH17 | ADAMTS14 | 0.668164 | 3 | 0 | 3 |
| DNAH17 | BASP1 | 0.668142 | 5 | 0 | 5 |
| DNAH17 | CNTROB | 0.666324 | 5 | 0 | 4 |
| DNAH17 | XAB2 | 0.664372 | 3 | 0 | 3 |
| DNAH17 | FBLN2 | 0.664041 | 3 | 0 | 3 |
| DNAH17 | ZNF707 | 0.663065 | 3 | 0 | 3 |
| DNAH17 | GSDMD | 0.662162 | 7 | 0 | 7 |
| DNAH17 | PLA2G7 | 0.661436 | 9 | 0 | 8 |
| DNAH17 | SNX10 | 0.660452 | 9 | 0 | 8 |
For details and further investigation, click here
