| Full name: erythrocyte membrane protein band 4.1 like 1 | Alias Symbol: KIAA0338|4.1N | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 2036 | HGNC ID: HGNC:3378 | Ensembl Gene: ENSG00000088367 | OMIM ID: 602879 |
| Drug and gene relationship at DGIdb | |||
EPB41L1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of EPB41L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPB41L1 | 2036 | 212339_at | -0.1022 | 0.8616 | |
| GSE20347 | EPB41L1 | 2036 | 212336_at | -0.6616 | 0.0358 | |
| GSE23400 | EPB41L1 | 2036 | 212339_at | -0.6437 | 0.0000 | |
| GSE26886 | EPB41L1 | 2036 | 212339_at | -1.3743 | 0.0013 | |
| GSE29001 | EPB41L1 | 2036 | 212339_at | -1.1579 | 0.0202 | |
| GSE38129 | EPB41L1 | 2036 | 212336_at | -0.6426 | 0.0042 | |
| GSE45670 | EPB41L1 | 2036 | 212339_at | -0.0343 | 0.9429 | |
| GSE53622 | EPB41L1 | 2036 | 209 | -0.7717 | 0.0000 | |
| GSE53624 | EPB41L1 | 2036 | 209 | -0.8827 | 0.0000 | |
| GSE63941 | EPB41L1 | 2036 | 212336_at | 0.5583 | 0.5597 | |
| GSE77861 | EPB41L1 | 2036 | 212339_at | -0.2274 | 0.6675 | |
| GSE97050 | EPB41L1 | 2036 | A_33_P3228510 | -0.3843 | 0.3673 | |
| SRP007169 | EPB41L1 | 2036 | RNAseq | 0.0510 | 0.9346 | |
| SRP008496 | EPB41L1 | 2036 | RNAseq | -0.2293 | 0.5715 | |
| SRP064894 | EPB41L1 | 2036 | RNAseq | -0.5785 | 0.0214 | |
| SRP133303 | EPB41L1 | 2036 | RNAseq | -0.3528 | 0.3448 | |
| SRP159526 | EPB41L1 | 2036 | RNAseq | -0.1153 | 0.7280 | |
| SRP193095 | EPB41L1 | 2036 | RNAseq | -0.2039 | 0.3604 | |
| SRP219564 | EPB41L1 | 2036 | RNAseq | -0.6881 | 0.0575 | |
| TCGA | EPB41L1 | 2036 | RNAseq | -0.4505 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EPB41L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPB41L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPB41L1 | 2036 | 14 | 1 | 15 | |
| GSE20123 | EPB41L1 | 2036 | 14 | 1 | 15 | |
| GSE43470 | EPB41L1 | 2036 | 12 | 0 | 31 | |
| GSE46452 | EPB41L1 | 2036 | 29 | 0 | 30 | |
| GSE47630 | EPB41L1 | 2036 | 24 | 0 | 16 | |
| GSE54993 | EPB41L1 | 2036 | 0 | 17 | 53 | |
| GSE54994 | EPB41L1 | 2036 | 24 | 0 | 29 | |
| GSE60625 | EPB41L1 | 2036 | 0 | 0 | 11 | |
| GSE74703 | EPB41L1 | 2036 | 11 | 0 | 25 | |
| GSE74704 | EPB41L1 | 2036 | 10 | 0 | 10 | |
| TCGA | EPB41L1 | 2036 | 49 | 3 | 44 |
Total number of gains: 187; Total number of losses: 22; Total Number of normals: 279.
Somatic mutations of EPB41L1:
Generating mutation plots.
Highly correlated genes for EPB41L1:
Showing top 20/321 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPB41L1 | LINC00960 | 0.678655 | 3 | 0 | 3 |
| EPB41L1 | SUSD4 | 0.659054 | 11 | 0 | 10 |
| EPB41L1 | CYP3A5 | 0.643333 | 9 | 0 | 8 |
| EPB41L1 | LRRC28 | 0.636078 | 3 | 0 | 3 |
| EPB41L1 | LNX1 | 0.632723 | 4 | 0 | 4 |
| EPB41L1 | RAPGEFL1 | 0.621303 | 12 | 0 | 10 |
| EPB41L1 | ELF3 | 0.616805 | 11 | 0 | 9 |
| EPB41L1 | CXCL17 | 0.615584 | 7 | 0 | 6 |
| EPB41L1 | CYP4B1 | 0.613772 | 10 | 0 | 9 |
| EPB41L1 | SIM2 | 0.607603 | 7 | 0 | 7 |
| EPB41L1 | SCNN1A | 0.606843 | 11 | 0 | 11 |
| EPB41L1 | PAFAH2 | 0.60643 | 6 | 0 | 4 |
| EPB41L1 | TP53INP2 | 0.603054 | 5 | 0 | 5 |
| EPB41L1 | ERBB2 | 0.601082 | 9 | 0 | 8 |
| EPB41L1 | DUOX2 | 0.597836 | 11 | 0 | 8 |
| EPB41L1 | NEBL | 0.597801 | 9 | 0 | 8 |
| EPB41L1 | SNX31 | 0.597763 | 6 | 0 | 5 |
| EPB41L1 | CEACAM6 | 0.593625 | 10 | 0 | 7 |
| EPB41L1 | GRHL1 | 0.593163 | 3 | 0 | 3 |
| EPB41L1 | NHP2 | 0.589658 | 4 | 0 | 4 |
For details and further investigation, click here
