| Full name: Fc fragment of IgG binding protein | Alias Symbol: FC(GAMMA)BP | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 8857 | HGNC ID: HGNC:13572 | Ensembl Gene: ENSG00000275395 | OMIM ID: 617553 |
| Drug and gene relationship at DGIdb | |||
Expression of FCGBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCGBP | 8857 | 203240_at | -0.5498 | 0.7276 | |
| GSE20347 | FCGBP | 8857 | 203240_at | -0.9730 | 0.0000 | |
| GSE23400 | FCGBP | 8857 | 203240_at | -0.6312 | 0.0000 | |
| GSE26886 | FCGBP | 8857 | 203240_at | -2.2921 | 0.0000 | |
| GSE29001 | FCGBP | 8857 | 203240_at | -0.4210 | 0.2737 | |
| GSE38129 | FCGBP | 8857 | 203240_at | -0.8884 | 0.0003 | |
| GSE45670 | FCGBP | 8857 | 203240_at | -0.3779 | 0.4075 | |
| GSE63941 | FCGBP | 8857 | 203240_at | 0.1705 | 0.5489 | |
| GSE77861 | FCGBP | 8857 | 203240_at | -0.9806 | 0.0114 | |
| GSE97050 | FCGBP | 8857 | A_23_P21495 | 0.1078 | 0.7232 | |
| SRP007169 | FCGBP | 8857 | RNAseq | -3.5352 | 0.0000 | |
| SRP008496 | FCGBP | 8857 | RNAseq | -3.5427 | 0.0000 | |
| SRP064894 | FCGBP | 8857 | RNAseq | -1.2364 | 0.0043 | |
| SRP133303 | FCGBP | 8857 | RNAseq | -1.1883 | 0.0286 | |
| SRP159526 | FCGBP | 8857 | RNAseq | -1.7194 | 0.0234 | |
| SRP193095 | FCGBP | 8857 | RNAseq | -2.6069 | 0.0000 | |
| SRP219564 | FCGBP | 8857 | RNAseq | -2.1791 | 0.0326 | |
| TCGA | FCGBP | 8857 | RNAseq | -0.6274 | 0.0058 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by FCGBP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FCGBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCGBP | 8857 | 7 | 4 | 19 | |
| GSE20123 | FCGBP | 8857 | 7 | 3 | 20 | |
| GSE43470 | FCGBP | 8857 | 3 | 10 | 30 | |
| GSE46452 | FCGBP | 8857 | 48 | 1 | 10 | |
| GSE47630 | FCGBP | 8857 | 9 | 5 | 26 | |
| GSE54993 | FCGBP | 8857 | 17 | 3 | 50 | |
| GSE54994 | FCGBP | 8857 | 8 | 9 | 36 | |
| GSE60625 | FCGBP | 8857 | 9 | 0 | 2 | |
| GSE74703 | FCGBP | 8857 | 3 | 7 | 26 | |
| GSE74704 | FCGBP | 8857 | 7 | 1 | 12 | |
| TCGA | FCGBP | 8857 | 14 | 16 | 66 |
Total number of gains: 132; Total number of losses: 59; Total Number of normals: 297.
Somatic mutations of FCGBP:
Generating mutation plots.
Highly correlated genes for FCGBP:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCGBP | CCL28 | 0.797547 | 3 | 0 | 3 |
| FCGBP | PITHD1 | 0.730714 | 3 | 0 | 3 |
| FCGBP | SPTLC3 | 0.710434 | 3 | 0 | 3 |
| FCGBP | MUC20 | 0.695298 | 4 | 0 | 3 |
| FCGBP | XBP1 | 0.691457 | 3 | 0 | 3 |
| FCGBP | ATG9B | 0.691 | 3 | 0 | 3 |
| FCGBP | RIPK3 | 0.689818 | 4 | 0 | 4 |
| FCGBP | SLC27A6 | 0.68951 | 3 | 0 | 3 |
| FCGBP | FAM3B | 0.684457 | 3 | 0 | 3 |
| FCGBP | SLC18B1 | 0.681686 | 3 | 0 | 3 |
| FCGBP | SLC44A2 | 0.679611 | 4 | 0 | 4 |
| FCGBP | ST6GALNAC1 | 0.675275 | 5 | 0 | 5 |
| FCGBP | RBM20 | 0.673096 | 4 | 0 | 4 |
| FCGBP | CHIC2 | 0.670559 | 5 | 0 | 4 |
| FCGBP | SLC9A8 | 0.670321 | 4 | 0 | 4 |
| FCGBP | LRG1 | 0.668108 | 5 | 0 | 4 |
| FCGBP | FAM174A | 0.666592 | 3 | 0 | 3 |
| FCGBP | PLEKHA7 | 0.666458 | 5 | 0 | 3 |
| FCGBP | RAB3D | 0.666093 | 4 | 0 | 3 |
| FCGBP | MPZL3 | 0.664926 | 4 | 0 | 3 |
For details and further investigation, click here
