| Full name: Kruppel like factor 12 | Alias Symbol: AP-2rep|HSPC122|AP2REP | ||
| Type: protein-coding gene | Cytoband: 13q22.1 | ||
| Entrez ID: 11278 | HGNC ID: HGNC:6346 | Ensembl Gene: ENSG00000118922 | OMIM ID: 607531 |
Expression of KLF12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF12 | 11278 | 227261_at | 0.0951 | 0.9394 | |
| GSE20347 | KLF12 | 11278 | 206966_s_at | 0.1133 | 0.3685 | |
| GSE23400 | KLF12 | 11278 | 206966_s_at | 0.0017 | 0.9611 | |
| GSE26886 | KLF12 | 11278 | 227261_at | 0.7756 | 0.0304 | |
| GSE29001 | KLF12 | 11278 | 214276_at | 0.1018 | 0.7004 | |
| GSE38129 | KLF12 | 11278 | 206966_s_at | 0.0413 | 0.7434 | |
| GSE45670 | KLF12 | 11278 | 227261_at | -0.7431 | 0.0487 | |
| GSE53622 | KLF12 | 11278 | 47166 | -0.0938 | 0.5675 | |
| GSE53624 | KLF12 | 11278 | 47166 | 0.3086 | 0.0036 | |
| GSE63941 | KLF12 | 11278 | 227261_at | -1.2194 | 0.2217 | |
| GSE77861 | KLF12 | 11278 | 206966_s_at | 0.0768 | 0.3038 | |
| GSE97050 | KLF12 | 11278 | A_23_P354805 | -0.3263 | 0.4296 | |
| SRP007169 | KLF12 | 11278 | RNAseq | 1.4968 | 0.0022 | |
| SRP008496 | KLF12 | 11278 | RNAseq | 1.7894 | 0.0000 | |
| SRP064894 | KLF12 | 11278 | RNAseq | 0.4099 | 0.0777 | |
| SRP133303 | KLF12 | 11278 | RNAseq | 0.4686 | 0.0496 | |
| SRP159526 | KLF12 | 11278 | RNAseq | 0.1148 | 0.7550 | |
| SRP193095 | KLF12 | 11278 | RNAseq | 0.4942 | 0.0282 | |
| SRP219564 | KLF12 | 11278 | RNAseq | 0.0338 | 0.9567 | |
| TCGA | KLF12 | 11278 | RNAseq | -0.2655 | 0.0271 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by KLF12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF12 | 11278 | 3 | 10 | 17 | |
| GSE20123 | KLF12 | 11278 | 3 | 9 | 18 | |
| GSE43470 | KLF12 | 11278 | 4 | 10 | 29 | |
| GSE46452 | KLF12 | 11278 | 0 | 32 | 27 | |
| GSE47630 | KLF12 | 11278 | 3 | 27 | 10 | |
| GSE54993 | KLF12 | 11278 | 11 | 3 | 56 | |
| GSE54994 | KLF12 | 11278 | 4 | 13 | 36 | |
| GSE60625 | KLF12 | 11278 | 0 | 3 | 8 | |
| GSE74703 | KLF12 | 11278 | 3 | 8 | 25 | |
| GSE74704 | KLF12 | 11278 | 1 | 8 | 11 | |
| TCGA | KLF12 | 11278 | 15 | 30 | 51 |
Total number of gains: 47; Total number of losses: 153; Total Number of normals: 288.
Somatic mutations of KLF12:
Generating mutation plots.
Highly correlated genes for KLF12:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF12 | DENND1A | 0.73731 | 3 | 0 | 3 |
| KLF12 | FOXP2 | 0.723749 | 3 | 0 | 3 |
| KLF12 | C3orf70 | 0.661664 | 4 | 0 | 4 |
| KLF12 | TRAK1 | 0.66046 | 3 | 0 | 3 |
| KLF12 | ANKRD23 | 0.643092 | 3 | 0 | 3 |
| KLF12 | YPEL1 | 0.640492 | 5 | 0 | 4 |
| KLF12 | CYP2U1 | 0.635994 | 6 | 0 | 4 |
| KLF12 | EGR2 | 0.632732 | 4 | 0 | 3 |
| KLF12 | AP1S2 | 0.632312 | 4 | 0 | 4 |
| KLF12 | CTSF | 0.631967 | 6 | 0 | 5 |
| KLF12 | PLEKHO1 | 0.630914 | 8 | 0 | 7 |
| KLF12 | IL17D | 0.62349 | 6 | 0 | 4 |
| KLF12 | GPRC5C | 0.622244 | 3 | 0 | 3 |
| KLF12 | RP9 | 0.62199 | 3 | 0 | 3 |
| KLF12 | LDLRAD4 | 0.621632 | 3 | 0 | 3 |
| KLF12 | ANKS3 | 0.619944 | 4 | 0 | 3 |
| KLF12 | ENOX1 | 0.615326 | 7 | 0 | 4 |
| KLF12 | ATP2B4 | 0.614404 | 4 | 0 | 3 |
| KLF12 | PKD2 | 0.613702 | 7 | 0 | 6 |
| KLF12 | CBX6 | 0.613636 | 6 | 0 | 5 |
For details and further investigation, click here
