Full name: gem nuclear organelle associated protein 8	Alias Symbol: FLJ20514
Type: protein-coding gene	Cytoband: Xp22.2
Entrez ID: 54960	HGNC ID: HGNC:26044	Ensembl Gene: ENSG00000046647	OMIM ID: 300962
Drug and gene relationship at DGIdb
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found 213/325 cell lines had fitness change in Project Score. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of GEMIN8:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	GEMIN8	54960	222854_s_at	-0.1891	0.7341	Show
GSE20347	GEMIN8	54960	219252_s_at	-0.3258	0.0002	Show
GSE23400	GEMIN8	54960	219252_s_at	-0.1335	0.0000	Show
GSE26886	GEMIN8	54960	230758_at	-0.2508	0.4651	Show
GSE29001	GEMIN8	54960	219252_s_at	-0.5224	0.0090	Show
GSE38129	GEMIN8	54960	219252_s_at	-0.4335	0.0000	Show
GSE45670	GEMIN8	54960	222854_s_at	-0.1206	0.3751	Show
GSE53622	GEMIN8	54960	72377	-0.2230	0.0007	Show
GSE53624	GEMIN8	54960	72377	-0.3669	0.0000	Show
GSE63941	GEMIN8	54960	222854_s_at	-0.5411	0.3205	Show
GSE77861	GEMIN8	54960	230758_at	-0.2284	0.0689	Show
GSE97050	GEMIN8	54960	A_24_P156576	-0.2595	0.2858	Show
SRP007169	GEMIN8	54960	RNAseq	-0.4862	0.3841	Show
SRP008496	GEMIN8	54960	RNAseq	-0.5039	0.2113	Show
SRP064894	GEMIN8	54960	RNAseq	-0.0182	0.9241	Show
SRP133303	GEMIN8	54960	RNAseq	-0.0618	0.7359	Show
SRP159526	GEMIN8	54960	RNAseq	-0.3727	0.0375	Show
SRP193095	GEMIN8	54960	RNAseq	-0.1448	0.1050	Show
SRP219564	GEMIN8	54960	RNAseq	-0.0841	0.7324	Show
TCGA	GEMIN8	54960	RNAseq	-0.1110	0.1109	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by GEMIN8 expression:

 

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Copy number change of GEMIN8:

 

No record found for this gene.

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Somatic mutations of GEMIN8:

 

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Highly correlated genes for GEMIN8:

 

Showing top 20/153 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
GEMIN8	PITHD1	0.624752	4	0	3
GEMIN8	WNK2	0.61685	3	0	3
GEMIN8	RNLS	0.615435	5	0	3
GEMIN8	RNF167	0.613683	5	0	3
GEMIN8	LURAP1	0.605937	3	0	3
GEMIN8	AKR7A2	0.605924	6	0	5
GEMIN8	NDUFS7	0.600813	5	0	3
GEMIN8	MID1	0.599262	5	0	3
GEMIN8	BLOC1S1	0.595116	7	0	5
GEMIN8	CENPC	0.593418	4	0	3
GEMIN8	PARP16	0.591728	4	0	3
GEMIN8	PCCA	0.590016	7	0	6
GEMIN8	RUNDC3B	0.588009	6	0	6
GEMIN8	PAX9	0.584127	5	0	3
GEMIN8	AKR7A3	0.58188	5	0	3
GEMIN8	NDRG2	0.578913	4	0	3
GEMIN8	CTNNBIP1	0.578321	7	0	5
GEMIN8	SLC7A10	0.57751	3	0	3
GEMIN8	PCBD1	0.576875	6	0	5
GEMIN8	FGA	0.575134	4	0	4

For details and further investigation, click here