| Full name: histatin 1 | Alias Symbol: HIS1 | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 3346 | HGNC ID: HGNC:5283 | Ensembl Gene: ENSG00000126550 | OMIM ID: 142701 |
| Drug and gene relationship at DGIdb | |||
Expression of HTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HTN1 | 3346 | 206639_x_at | -0.2817 | 0.6255 | |
| GSE20347 | HTN1 | 3346 | 206639_x_at | 0.0718 | 0.1864 | |
| GSE23400 | HTN1 | 3346 | 206639_x_at | 0.0431 | 0.1760 | |
| GSE26886 | HTN1 | 3346 | 206639_x_at | 0.0857 | 0.3311 | |
| GSE29001 | HTN1 | 3346 | 206639_x_at | -0.0215 | 0.9157 | |
| GSE38129 | HTN1 | 3346 | 206639_x_at | 0.0730 | 0.3042 | |
| GSE45670 | HTN1 | 3346 | 206639_x_at | -0.1567 | 0.0591 | |
| GSE53622 | HTN1 | 3346 | 98862 | -0.2866 | 0.1359 | |
| GSE53624 | HTN1 | 3346 | 98862 | 0.0263 | 0.9059 | |
| GSE63941 | HTN1 | 3346 | 206639_x_at | -0.2503 | 0.0193 | |
| GSE77861 | HTN1 | 3346 | 206639_x_at | -0.0084 | 0.9395 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HTN1 | 3346 | 0 | 10 | 20 | |
| GSE20123 | HTN1 | 3346 | 0 | 11 | 19 | |
| GSE43470 | HTN1 | 3346 | 0 | 13 | 30 | |
| GSE46452 | HTN1 | 3346 | 2 | 35 | 22 | |
| GSE47630 | HTN1 | 3346 | 1 | 18 | 21 | |
| GSE54993 | HTN1 | 3346 | 7 | 0 | 63 | |
| GSE54994 | HTN1 | 3346 | 1 | 9 | 43 | |
| GSE60625 | HTN1 | 3346 | 0 | 0 | 11 | |
| GSE74703 | HTN1 | 3346 | 0 | 11 | 25 | |
| GSE74704 | HTN1 | 3346 | 0 | 7 | 13 | |
| TCGA | HTN1 | 3346 | 15 | 28 | 53 |
Total number of gains: 26; Total number of losses: 142; Total Number of normals: 320.
Somatic mutations of HTN1:
Generating mutation plots.
Highly correlated genes for HTN1:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HTN1 | CHST4 | 0.757606 | 3 | 0 | 3 |
| HTN1 | DNASE2B | 0.7362 | 3 | 0 | 3 |
| HTN1 | LCT | 0.685285 | 3 | 0 | 3 |
| HTN1 | CLC | 0.681577 | 4 | 0 | 4 |
| HTN1 | ZMAT4 | 0.66934 | 3 | 0 | 3 |
| HTN1 | NXPE4 | 0.667176 | 4 | 0 | 3 |
| HTN1 | SYT13 | 0.658834 | 3 | 0 | 3 |
| HTN1 | CYSLTR2 | 0.654693 | 3 | 0 | 3 |
| HTN1 | ADAMTS12 | 0.649774 | 3 | 0 | 3 |
| HTN1 | ADAM18 | 0.648565 | 3 | 0 | 3 |
| HTN1 | PTPRN2 | 0.64373 | 4 | 0 | 3 |
| HTN1 | LEFTY1 | 0.642148 | 3 | 0 | 3 |
| HTN1 | CCL16 | 0.637414 | 3 | 0 | 3 |
| HTN1 | C16orf89 | 0.635368 | 3 | 0 | 3 |
| HTN1 | MAB21L2 | 0.611828 | 5 | 0 | 4 |
| HTN1 | PDE1C | 0.607694 | 5 | 0 | 3 |
| HTN1 | CD4 | 0.603051 | 3 | 0 | 3 |
| HTN1 | HTR2A | 0.595765 | 4 | 0 | 3 |
| HTN1 | MASP1 | 0.59523 | 3 | 0 | 3 |
| HTN1 | KERA | 0.595222 | 4 | 0 | 3 |
For details and further investigation, click here
