| Full name: LY6/PLAUR domain containing 2 | Alias Symbol: RGTR430|UNQ430 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 137797 | HGNC ID: HGNC:25215 | Ensembl Gene: ENSG00000197353 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LYPD2 | 137797 | 80111 | -4.0609 | 0.0000 | |
| GSE53624 | LYPD2 | 137797 | 80111 | -4.5736 | 0.0000 | |
| SRP007169 | LYPD2 | 137797 | RNAseq | -5.9478 | 0.0004 | |
| SRP008496 | LYPD2 | 137797 | RNAseq | -5.7909 | 0.0000 | |
| SRP064894 | LYPD2 | 137797 | RNAseq | -4.7533 | 0.0000 | |
| SRP133303 | LYPD2 | 137797 | RNAseq | -6.1281 | 0.0000 | |
| SRP159526 | LYPD2 | 137797 | RNAseq | -5.8934 | 0.0000 | |
| TCGA | LYPD2 | 137797 | RNAseq | -0.4726 | 0.4987 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by LYPD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD2 | 137797 | 16 | 1 | 13 | |
| GSE20123 | LYPD2 | 137797 | 17 | 1 | 12 | |
| GSE43470 | LYPD2 | 137797 | 17 | 2 | 24 | |
| GSE46452 | LYPD2 | 137797 | 27 | 0 | 32 | |
| GSE47630 | LYPD2 | 137797 | 23 | 1 | 16 | |
| GSE54993 | LYPD2 | 137797 | 0 | 25 | 45 | |
| GSE54994 | LYPD2 | 137797 | 39 | 1 | 13 | |
| GSE60625 | LYPD2 | 137797 | 3 | 4 | 4 | |
| GSE74703 | LYPD2 | 137797 | 15 | 1 | 20 | |
| GSE74704 | LYPD2 | 137797 | 10 | 0 | 10 | |
| TCGA | LYPD2 | 137797 | 63 | 2 | 31 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of LYPD2:
Generating mutation plots.
Highly correlated genes for LYPD2:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD2 | PRSS27 | 0.904912 | 3 | 0 | 3 |
| LYPD2 | LYNX1 | 0.866207 | 3 | 0 | 3 |
| LYPD2 | SPINK5 | 0.862985 | 3 | 0 | 3 |
| LYPD2 | MUC21 | 0.86196 | 3 | 0 | 3 |
| LYPD2 | SCEL | 0.846781 | 3 | 0 | 3 |
| LYPD2 | SLURP1 | 0.846119 | 3 | 0 | 3 |
| LYPD2 | CLCA4 | 0.83871 | 3 | 0 | 3 |
| LYPD2 | CAPN14 | 0.836351 | 3 | 0 | 3 |
| LYPD2 | EPS8L1 | 0.835861 | 3 | 0 | 3 |
| LYPD2 | FAM3D | 0.833643 | 3 | 0 | 3 |
| LYPD2 | KLK13 | 0.832089 | 3 | 0 | 3 |
| LYPD2 | NCCRP1 | 0.828535 | 3 | 0 | 3 |
| LYPD2 | TMPRSS11B | 0.826472 | 3 | 0 | 3 |
| LYPD2 | HCG22 | 0.81871 | 3 | 0 | 3 |
| LYPD2 | KRT78 | 0.815917 | 3 | 0 | 3 |
| LYPD2 | PPL | 0.812255 | 3 | 0 | 3 |
| LYPD2 | CRNN | 0.801994 | 3 | 0 | 3 |
| LYPD2 | KRT4 | 0.7986 | 3 | 0 | 3 |
| LYPD2 | A2ML1 | 0.794846 | 3 | 0 | 3 |
| LYPD2 | CEACAM5 | 0.793351 | 3 | 0 | 3 |
For details and further investigation, click here
