ZNF367

 

Full name: zinc finger protein 367 Alias Symbol: FLJ33970
Type: protein-coding gene Cytoband: 9q22.32
Entrez ID: 195828 HGNC ID: HGNC:18320 Ensembl Gene: ENSG00000165244 OMIM ID: 610160
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ZNF367:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF367 195828 229551_x_at 0.6137 0.2080
GSE26886 ZNF367 195828 229551_x_at 0.5010 0.0749
GSE45670 ZNF367 195828 229551_x_at 0.6303 0.0134
GSE53622 ZNF367 195828 37281 1.0308 0.0000
GSE53624 ZNF367 195828 37281 1.2369 0.0000
GSE63941 ZNF367 195828 229551_x_at 2.2756 0.0048
GSE77861 ZNF367 195828 229551_x_at 0.4664 0.0292
GSE97050 ZNF367 195828 A_23_P410625 0.5568 0.2151
SRP007169 ZNF367 195828 RNAseq 1.5994 0.0019
SRP008496 ZNF367 195828 RNAseq 1.3358 0.0006
SRP064894 ZNF367 195828 RNAseq 0.9764 0.0064
SRP133303 ZNF367 195828 RNAseq 0.9703 0.0000
SRP159526 ZNF367 195828 RNAseq 1.0560 0.0113
SRP193095 ZNF367 195828 RNAseq 0.6566 0.0001
SRP219564 ZNF367 195828 RNAseq 0.8531 0.0202
TCGA ZNF367 195828 RNAseq 0.6295 0.0000

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by ZNF367 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNF367:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF367 195828 6 8 16
GSE20123 ZNF367 195828 6 7 17
GSE43470 ZNF367 195828 6 3 34
GSE46452 ZNF367 195828 6 14 39
GSE47630 ZNF367 195828 1 17 22
GSE54993 ZNF367 195828 3 2 65
GSE54994 ZNF367 195828 8 11 34
GSE60625 ZNF367 195828 0 0 11
GSE74703 ZNF367 195828 5 3 28
GSE74704 ZNF367 195828 3 5 12
TCGA ZNF367 195828 25 23 48

Total number of gains: 69; Total number of losses: 93; Total Number of normals: 326.  

 

Somatic mutations of ZNF367:

 

Generating mutation plots.

 

Highly correlated genes for ZNF367:

 

Showing top 20/1105 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF367CDC450.755392707
ZNF367KIF140.748943808
ZNF367UHRF10.748287807
ZNF367DTL0.744081808
ZNF367HJURP0.743722707
ZNF367CDK10.741175808
ZNF367SLC19A10.741168303
ZNF367CDCA30.739533707
ZNF367TMEM2160.734135303
ZNF367MKI670.733872707
ZNF367HELLS0.7335808
ZNF367KIF2C0.731876707
ZNF367POLA20.728049707
ZNF367RNASEH2A0.726954707
ZNF367BRIP10.726729808
ZNF367CDT10.726344707
ZNF367NEK20.726295707
ZNF367ZWINT0.726103606
ZNF367RFC40.720112807
ZNF367RFC30.720048808

For details and further investigation, click here