| Full name: RNA polymerase II subunit F | Alias Symbol: RPB6|HRBP14.4 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 5435 | HGNC ID: HGNC:9193 | Ensembl Gene: ENSG00000100142 | OMIM ID: 604414 |
| Drug and gene relationship at DGIdb | |||
Expression of POLR2F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POLR2F | 5435 | 209511_at | 0.2508 | 0.2492 | |
| GSE20347 | POLR2F | 5435 | 209511_at | 0.3374 | 0.0264 | |
| GSE23400 | POLR2F | 5435 | 209511_at | 0.3289 | 0.0000 | |
| GSE26886 | POLR2F | 5435 | 209511_at | 0.4268 | 0.0035 | |
| GSE29001 | POLR2F | 5435 | 209511_at | 0.4438 | 0.0825 | |
| GSE38129 | POLR2F | 5435 | 209511_at | 0.3700 | 0.0017 | |
| GSE45670 | POLR2F | 5435 | 209511_at | 0.2923 | 0.0641 | |
| GSE53622 | POLR2F | 5435 | 28345 | 0.2226 | 0.0002 | |
| GSE53624 | POLR2F | 5435 | 28345 | 0.6300 | 0.0000 | |
| GSE63941 | POLR2F | 5435 | 209511_at | -0.0448 | 0.9298 | |
| GSE77861 | POLR2F | 5435 | 209511_at | 0.4475 | 0.0406 | |
| GSE97050 | POLR2F | 5435 | A_33_P3318960 | -0.0124 | 0.9589 | |
| SRP007169 | POLR2F | 5435 | RNAseq | -0.0867 | 0.8375 | |
| SRP008496 | POLR2F | 5435 | RNAseq | -0.4755 | 0.1605 | |
| SRP064894 | POLR2F | 5435 | RNAseq | 0.7970 | 0.0160 | |
| SRP133303 | POLR2F | 5435 | RNAseq | 0.2091 | 0.1099 | |
| SRP159526 | POLR2F | 5435 | RNAseq | 0.8509 | 0.0097 | |
| SRP193095 | POLR2F | 5435 | RNAseq | 0.1049 | 0.4251 | |
| SRP219564 | POLR2F | 5435 | RNAseq | 0.3833 | 0.3158 | |
| TCGA | POLR2F | 5435 | RNAseq | 0.1395 | 0.0146 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POLR2F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POLR2F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POLR2F | 5435 | 6 | 5 | 19 | |
| GSE20123 | POLR2F | 5435 | 6 | 4 | 20 | |
| GSE43470 | POLR2F | 5435 | 5 | 6 | 32 | |
| GSE46452 | POLR2F | 5435 | 32 | 2 | 25 | |
| GSE47630 | POLR2F | 5435 | 9 | 4 | 27 | |
| GSE54993 | POLR2F | 5435 | 3 | 6 | 61 | |
| GSE54994 | POLR2F | 5435 | 9 | 7 | 37 | |
| GSE60625 | POLR2F | 5435 | 5 | 0 | 6 | |
| GSE74703 | POLR2F | 5435 | 5 | 4 | 27 | |
| GSE74704 | POLR2F | 5435 | 3 | 2 | 15 | |
| TCGA | POLR2F | 5435 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 55; Total Number of normals: 323.
Somatic mutations of POLR2F:
Generating mutation plots.
Highly correlated genes for POLR2F:
Showing top 20/617 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POLR2F | SHISA2 | 0.681681 | 5 | 0 | 5 |
| POLR2F | PES1 | 0.681297 | 10 | 0 | 10 |
| POLR2F | THOC5 | 0.664321 | 11 | 0 | 11 |
| POLR2F | IMP4 | 0.662303 | 10 | 0 | 9 |
| POLR2F | WNT2 | 0.658127 | 5 | 0 | 4 |
| POLR2F | CCT7 | 0.657281 | 11 | 0 | 9 |
| POLR2F | HAS3 | 0.652324 | 3 | 0 | 3 |
| POLR2F | XRCC6 | 0.650046 | 11 | 0 | 9 |
| POLR2F | ANAPC11 | 0.648939 | 4 | 0 | 4 |
| POLR2F | RPS19BP1 | 0.647817 | 7 | 0 | 6 |
| POLR2F | ADSL | 0.64735 | 12 | 0 | 9 |
| POLR2F | PFDN2 | 0.647004 | 10 | 0 | 9 |
| POLR2F | AIFM1 | 0.644475 | 6 | 0 | 4 |
| POLR2F | DNAJB11 | 0.642255 | 6 | 0 | 5 |
| POLR2F | CHRNA5 | 0.641478 | 5 | 0 | 4 |
| POLR2F | CDC45 | 0.639661 | 10 | 0 | 10 |
| POLR2F | PHF5A | 0.639508 | 8 | 0 | 7 |
| POLR2F | LAS1L | 0.63636 | 5 | 0 | 5 |
| POLR2F | CCT4 | 0.636354 | 9 | 0 | 8 |
| POLR2F | PSMD11 | 0.635569 | 10 | 0 | 8 |
For details and further investigation, click here
