| Full name: anoctamin 1 | Alias Symbol: TAOS2|FLJ10261|DOG1 | ||
| Type: protein-coding gene | Cytoband: 11q13.3 | ||
| Entrez ID: 55107 | HGNC ID: HGNC:21625 | Ensembl Gene: ENSG00000131620 | OMIM ID: 610108 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO1 | 55107 | 218804_at | 2.8284 | 0.1006 | |
| GSE20347 | ANO1 | 55107 | 218804_at | 3.5934 | 0.0000 | |
| GSE23400 | ANO1 | 55107 | 218804_at | 1.6694 | 0.0000 | |
| GSE26886 | ANO1 | 55107 | 218804_at | 3.5794 | 0.0000 | |
| GSE29001 | ANO1 | 55107 | 218804_at | 3.2059 | 0.0001 | |
| GSE38129 | ANO1 | 55107 | 218804_at | 3.0076 | 0.0000 | |
| GSE45670 | ANO1 | 55107 | 218804_at | 2.5884 | 0.0009 | |
| GSE53622 | ANO1 | 55107 | 42801 | 2.5868 | 0.0000 | |
| GSE53624 | ANO1 | 55107 | 42801 | 2.6977 | 0.0000 | |
| GSE63941 | ANO1 | 55107 | 1555269_a_at | 1.7276 | 0.2046 | |
| GSE77861 | ANO1 | 55107 | 1555269_a_at | 0.7440 | 0.3020 | |
| GSE97050 | ANO1 | 55107 | A_24_P87036 | 2.0276 | 0.1834 | |
| SRP007169 | ANO1 | 55107 | RNAseq | 6.0179 | 0.0001 | |
| SRP008496 | ANO1 | 55107 | RNAseq | 5.3960 | 0.0000 | |
| SRP064894 | ANO1 | 55107 | RNAseq | 1.8511 | 0.0000 | |
| SRP133303 | ANO1 | 55107 | RNAseq | 3.6901 | 0.0000 | |
| SRP159526 | ANO1 | 55107 | RNAseq | 5.7006 | 0.0000 | |
| SRP193095 | ANO1 | 55107 | RNAseq | 3.7515 | 0.0000 | |
| SRP219564 | ANO1 | 55107 | RNAseq | 3.4780 | 0.0011 | |
| TCGA | ANO1 | 55107 | RNAseq | 0.5481 | 0.0006 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by ANO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO1 | 55107 | 20 | 1 | 9 | |
| GSE20123 | ANO1 | 55107 | 20 | 1 | 9 | |
| GSE43470 | ANO1 | 55107 | 16 | 2 | 25 | |
| GSE46452 | ANO1 | 55107 | 35 | 2 | 22 | |
| GSE47630 | ANO1 | 55107 | 19 | 1 | 20 | |
| GSE54993 | ANO1 | 55107 | 1 | 25 | 44 | |
| GSE54994 | ANO1 | 55107 | 28 | 3 | 22 | |
| GSE60625 | ANO1 | 55107 | 0 | 8 | 3 | |
| GSE74703 | ANO1 | 55107 | 13 | 1 | 22 | |
| GSE74704 | ANO1 | 55107 | 13 | 0 | 7 | |
| TCGA | ANO1 | 55107 | 64 | 2 | 30 |
Total number of gains: 229; Total number of losses: 46; Total Number of normals: 213.
Somatic mutations of ANO1:
Generating mutation plots.
Highly correlated genes for ANO1:
Showing top 20/1212 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO1 | FADD | 0.798028 | 11 | 0 | 11 |
| ANO1 | PPFIA1 | 0.79142 | 13 | 0 | 13 |
| ANO1 | SCYL1 | 0.754728 | 3 | 0 | 3 |
| ANO1 | PMEPA1 | 0.711272 | 10 | 0 | 9 |
| ANO1 | CD276 | 0.701733 | 4 | 0 | 4 |
| ANO1 | CTHRC1 | 0.691803 | 6 | 0 | 6 |
| ANO1 | SSPN | 0.68967 | 3 | 0 | 3 |
| ANO1 | WDR54 | 0.686805 | 6 | 0 | 6 |
| ANO1 | SNX10 | 0.682125 | 10 | 0 | 9 |
| ANO1 | PLXNA1 | 0.678096 | 11 | 0 | 10 |
| ANO1 | COL5A2 | 0.676776 | 10 | 0 | 10 |
| ANO1 | HOXD10 | 0.675088 | 10 | 0 | 10 |
| ANO1 | GFM1 | 0.674547 | 5 | 0 | 5 |
| ANO1 | SERPINH1 | 0.672993 | 10 | 0 | 9 |
| ANO1 | ACVR1 | 0.671342 | 11 | 0 | 10 |
| ANO1 | PLAU | 0.669612 | 11 | 0 | 10 |
| ANO1 | KNSTRN | 0.666523 | 6 | 0 | 5 |
| ANO1 | MRGBP | 0.664439 | 8 | 0 | 8 |
| ANO1 | SNAI2 | 0.664324 | 8 | 0 | 7 |
| ANO1 | TTYH3 | 0.663399 | 6 | 0 | 5 |
For details and further investigation, click here
