| Full name: proteasome assembly chaperone 1 | Alias Symbol: c21-LRP|LRPC21|PAC1 | ||
| Type: protein-coding gene | Cytoband: 21q22.2 | ||
| Entrez ID: 8624 | HGNC ID: HGNC:3043 | Ensembl Gene: ENSG00000183527 | OMIM ID: 605296 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSMG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMG1 | 8624 | 203405_at | 0.2871 | 0.5095 | |
| GSE20347 | PSMG1 | 8624 | 203405_at | 0.1269 | 0.5799 | |
| GSE23400 | PSMG1 | 8624 | 203405_at | 0.5616 | 0.0000 | |
| GSE26886 | PSMG1 | 8624 | 203405_at | -0.0233 | 0.9577 | |
| GSE29001 | PSMG1 | 8624 | 203405_at | 0.3996 | 0.3625 | |
| GSE38129 | PSMG1 | 8624 | 203405_at | 0.4361 | 0.0197 | |
| GSE45670 | PSMG1 | 8624 | 203405_at | 0.2930 | 0.1498 | |
| GSE53622 | PSMG1 | 8624 | 87950 | 0.1504 | 0.0545 | |
| GSE53624 | PSMG1 | 8624 | 87950 | 0.4103 | 0.0000 | |
| GSE63941 | PSMG1 | 8624 | 203405_at | 0.1891 | 0.7518 | |
| GSE77861 | PSMG1 | 8624 | 203405_at | -0.1260 | 0.6861 | |
| GSE97050 | PSMG1 | 8624 | A_23_P68717 | 0.2455 | 0.3835 | |
| SRP007169 | PSMG1 | 8624 | RNAseq | -0.1169 | 0.7890 | |
| SRP008496 | PSMG1 | 8624 | RNAseq | -0.1901 | 0.5300 | |
| SRP064894 | PSMG1 | 8624 | RNAseq | 0.6037 | 0.0190 | |
| SRP133303 | PSMG1 | 8624 | RNAseq | 0.1165 | 0.5502 | |
| SRP159526 | PSMG1 | 8624 | RNAseq | -0.0402 | 0.8750 | |
| SRP193095 | PSMG1 | 8624 | RNAseq | 0.0356 | 0.8331 | |
| SRP219564 | PSMG1 | 8624 | RNAseq | 0.1935 | 0.6050 | |
| TCGA | PSMG1 | 8624 | RNAseq | 0.3254 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMG1 | 8624 | 2 | 9 | 19 | |
| GSE20123 | PSMG1 | 8624 | 2 | 10 | 18 | |
| GSE43470 | PSMG1 | 8624 | 0 | 10 | 33 | |
| GSE46452 | PSMG1 | 8624 | 1 | 21 | 37 | |
| GSE47630 | PSMG1 | 8624 | 6 | 17 | 17 | |
| GSE54993 | PSMG1 | 8624 | 8 | 1 | 61 | |
| GSE54994 | PSMG1 | 8624 | 3 | 9 | 41 | |
| GSE60625 | PSMG1 | 8624 | 0 | 0 | 11 | |
| GSE74703 | PSMG1 | 8624 | 0 | 8 | 28 | |
| GSE74704 | PSMG1 | 8624 | 1 | 6 | 13 | |
| TCGA | PSMG1 | 8624 | 8 | 41 | 47 |
Total number of gains: 31; Total number of losses: 132; Total Number of normals: 325.
Somatic mutations of PSMG1:
Generating mutation plots.
Highly correlated genes for PSMG1:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMG1 | GART | 0.61764 | 12 | 0 | 9 |
| PSMG1 | GINS3 | 0.614415 | 5 | 0 | 4 |
| PSMG1 | DAGLB | 0.596182 | 3 | 0 | 3 |
| PSMG1 | PPP1R14B | 0.59126 | 6 | 0 | 4 |
| PSMG1 | DONSON | 0.588629 | 11 | 0 | 7 |
| PSMG1 | RACGAP1 | 0.587909 | 6 | 0 | 5 |
| PSMG1 | UBXN8 | 0.582805 | 5 | 0 | 3 |
| PSMG1 | RFC5 | 0.58227 | 4 | 0 | 4 |
| PSMG1 | TMX1 | 0.577415 | 6 | 0 | 4 |
| PSMG1 | SS18L1 | 0.573988 | 3 | 0 | 3 |
| PSMG1 | LINC00958 | 0.57378 | 3 | 0 | 3 |
| PSMG1 | CLPB | 0.572758 | 4 | 0 | 3 |
| PSMG1 | FERMT1 | 0.572716 | 8 | 0 | 6 |
| PSMG1 | SLBP | 0.569314 | 6 | 0 | 4 |
| PSMG1 | PDXK | 0.569236 | 5 | 0 | 4 |
| PSMG1 | PDSS1 | 0.569023 | 8 | 0 | 6 |
| PSMG1 | HPRT1 | 0.568449 | 8 | 0 | 5 |
| PSMG1 | NUP37 | 0.562343 | 10 | 0 | 8 |
| PSMG1 | FBXL6 | 0.56214 | 6 | 0 | 5 |
| PSMG1 | ALG8 | 0.560388 | 4 | 0 | 3 |
For details and further investigation, click here
