| Full name: RAS like family 11 member A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q12.2 | ||
| Entrez ID: 387496 | HGNC ID: HGNC:23802 | Ensembl Gene: ENSG00000122035 | OMIM ID: 612403 |
| Drug and gene relationship at DGIdb | |||
Expression of RASL11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASL11A | 387496 | 238353_at | -0.1736 | 0.5428 | |
| GSE26886 | RASL11A | 387496 | 238353_at | 0.1099 | 0.3050 | |
| GSE45670 | RASL11A | 387496 | 238353_at | -0.8880 | 0.0001 | |
| GSE53622 | RASL11A | 387496 | 50228 | -1.6052 | 0.0000 | |
| GSE53624 | RASL11A | 387496 | 50228 | -1.2249 | 0.0000 | |
| GSE63941 | RASL11A | 387496 | 238353_at | -1.2737 | 0.0002 | |
| GSE77861 | RASL11A | 387496 | 238353_at | -0.0923 | 0.4377 | |
| GSE97050 | RASL11A | 387496 | A_23_P14124 | -0.3334 | 0.5622 | |
| SRP007169 | RASL11A | 387496 | RNAseq | 0.7813 | 0.3619 | |
| SRP008496 | RASL11A | 387496 | RNAseq | 0.4628 | 0.4483 | |
| SRP064894 | RASL11A | 387496 | RNAseq | -0.5955 | 0.0954 | |
| SRP133303 | RASL11A | 387496 | RNAseq | -0.5798 | 0.2219 | |
| SRP159526 | RASL11A | 387496 | RNAseq | -0.4987 | 0.4357 | |
| SRP193095 | RASL11A | 387496 | RNAseq | -0.1493 | 0.5711 | |
| SRP219564 | RASL11A | 387496 | RNAseq | -1.2626 | 0.1345 | |
| TCGA | RASL11A | 387496 | RNAseq | -0.5547 | 0.0228 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RASL11A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASL11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASL11A | 387496 | 1 | 13 | 16 | |
| GSE20123 | RASL11A | 387496 | 1 | 12 | 17 | |
| GSE43470 | RASL11A | 387496 | 2 | 12 | 29 | |
| GSE46452 | RASL11A | 387496 | 0 | 33 | 26 | |
| GSE47630 | RASL11A | 387496 | 3 | 26 | 11 | |
| GSE54993 | RASL11A | 387496 | 11 | 2 | 57 | |
| GSE54994 | RASL11A | 387496 | 1 | 13 | 39 | |
| GSE60625 | RASL11A | 387496 | 0 | 3 | 8 | |
| GSE74703 | RASL11A | 387496 | 2 | 9 | 25 | |
| GSE74704 | RASL11A | 387496 | 0 | 10 | 10 | |
| TCGA | RASL11A | 387496 | 6 | 41 | 49 |
Total number of gains: 27; Total number of losses: 174; Total Number of normals: 287.
Somatic mutations of RASL11A:
Generating mutation plots.
Highly correlated genes for RASL11A:
Showing top 20/461 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASL11A | SORCS1 | 0.774978 | 3 | 0 | 3 |
| RASL11A | CYP21A2 | 0.759425 | 3 | 0 | 3 |
| RASL11A | PCSK2 | 0.759309 | 3 | 0 | 3 |
| RASL11A | BHMT2 | 0.750223 | 5 | 0 | 5 |
| RASL11A | CBX7 | 0.747544 | 4 | 0 | 4 |
| RASL11A | NEGR1 | 0.734858 | 5 | 0 | 5 |
| RASL11A | RBPMS2 | 0.732123 | 4 | 0 | 4 |
| RASL11A | CHRDL1 | 0.730902 | 3 | 0 | 3 |
| RASL11A | SLITRK3 | 0.729795 | 4 | 0 | 4 |
| RASL11A | SGCA | 0.72271 | 4 | 0 | 4 |
| RASL11A | SMOC2 | 0.71872 | 4 | 0 | 4 |
| RASL11A | PYGM | 0.71871 | 4 | 0 | 4 |
| RASL11A | PDE5A | 0.717545 | 5 | 0 | 5 |
| RASL11A | TGFBR3 | 0.716503 | 4 | 0 | 4 |
| RASL11A | ITGA7 | 0.716496 | 4 | 0 | 4 |
| RASL11A | MOAP1 | 0.71213 | 4 | 0 | 4 |
| RASL11A | RCAN2 | 0.709995 | 5 | 0 | 5 |
| RASL11A | ANGPTL1 | 0.708705 | 4 | 0 | 4 |
| RASL11A | PGR | 0.706438 | 4 | 0 | 4 |
| RASL11A | MRVI1 | 0.704527 | 5 | 0 | 5 |
For details and further investigation, click here
