| Full name: ring finger protein 25 | Alias Symbol: AO7|FLJ13906 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 64320 | HGNC ID: HGNC:14662 | Ensembl Gene: ENSG00000163481 | OMIM ID: 616014 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNF25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF25 | 64320 | 218861_at | -0.0534 | 0.9245 | |
| GSE20347 | RNF25 | 64320 | 218861_at | -0.2900 | 0.0001 | |
| GSE23400 | RNF25 | 64320 | 218861_at | -0.0333 | 0.3471 | |
| GSE26886 | RNF25 | 64320 | 218861_at | 0.4219 | 0.0330 | |
| GSE29001 | RNF25 | 64320 | 218861_at | 0.0866 | 0.6507 | |
| GSE38129 | RNF25 | 64320 | 218861_at | -0.1858 | 0.0487 | |
| GSE45670 | RNF25 | 64320 | 218861_at | -0.0594 | 0.6846 | |
| GSE53622 | RNF25 | 64320 | 41864 | 0.2587 | 0.0000 | |
| GSE53624 | RNF25 | 64320 | 41864 | 0.1411 | 0.0120 | |
| GSE63941 | RNF25 | 64320 | 218861_at | -0.0631 | 0.8596 | |
| GSE77861 | RNF25 | 64320 | 218861_at | 0.0577 | 0.7781 | |
| GSE97050 | RNF25 | 64320 | A_23_P39656 | 0.2540 | 0.2917 | |
| SRP007169 | RNF25 | 64320 | RNAseq | -0.1979 | 0.6256 | |
| SRP008496 | RNF25 | 64320 | RNAseq | -0.4876 | 0.0372 | |
| SRP064894 | RNF25 | 64320 | RNAseq | 0.5054 | 0.0274 | |
| SRP133303 | RNF25 | 64320 | RNAseq | 0.1231 | 0.4877 | |
| SRP159526 | RNF25 | 64320 | RNAseq | 0.3313 | 0.2449 | |
| SRP193095 | RNF25 | 64320 | RNAseq | 0.1057 | 0.3222 | |
| SRP219564 | RNF25 | 64320 | RNAseq | 0.1153 | 0.6739 | |
| TCGA | RNF25 | 64320 | RNAseq | 0.0386 | 0.5162 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF25 | 64320 | 1 | 14 | 15 | |
| GSE20123 | RNF25 | 64320 | 1 | 13 | 16 | |
| GSE43470 | RNF25 | 64320 | 1 | 7 | 35 | |
| GSE46452 | RNF25 | 64320 | 0 | 5 | 54 | |
| GSE47630 | RNF25 | 64320 | 4 | 5 | 31 | |
| GSE54993 | RNF25 | 64320 | 1 | 2 | 67 | |
| GSE54994 | RNF25 | 64320 | 8 | 10 | 35 | |
| GSE60625 | RNF25 | 64320 | 0 | 3 | 8 | |
| GSE74703 | RNF25 | 64320 | 1 | 5 | 30 | |
| GSE74704 | RNF25 | 64320 | 1 | 7 | 12 | |
| TCGA | RNF25 | 64320 | 11 | 27 | 58 |
Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.
Somatic mutations of RNF25:
Generating mutation plots.
Highly correlated genes for RNF25:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF25 | LRRC8A | 0.734812 | 3 | 0 | 3 |
| RNF25 | METTL22 | 0.710987 | 4 | 0 | 4 |
| RNF25 | RELA | 0.708926 | 3 | 0 | 3 |
| RNF25 | DEXI | 0.678878 | 3 | 0 | 3 |
| RNF25 | PHLDA3 | 0.669749 | 3 | 0 | 3 |
| RNF25 | LRRC42 | 0.630566 | 4 | 0 | 3 |
| RNF25 | DRAP1 | 0.629459 | 4 | 0 | 3 |
| RNF25 | NACC1 | 0.629409 | 3 | 0 | 3 |
| RNF25 | SERPINB8 | 0.625106 | 3 | 0 | 3 |
| RNF25 | TRIM61 | 0.623692 | 3 | 0 | 3 |
| RNF25 | HECTD3 | 0.622592 | 3 | 0 | 3 |
| RNF25 | DDX10 | 0.617298 | 3 | 0 | 3 |
| RNF25 | PLK2 | 0.61465 | 3 | 0 | 3 |
| RNF25 | EIF2B3 | 0.613343 | 4 | 0 | 3 |
| RNF25 | DHX16 | 0.609615 | 4 | 0 | 3 |
| RNF25 | HSPBP1 | 0.609225 | 3 | 0 | 3 |
| RNF25 | RRAGA | 0.606496 | 3 | 0 | 3 |
| RNF25 | KCNRG | 0.606171 | 3 | 0 | 3 |
| RNF25 | PDE6D | 0.606116 | 4 | 0 | 4 |
| RNF25 | F2RL1 | 0.604839 | 3 | 0 | 3 |
For details and further investigation, click here
