| Full name: receptor tyrosine kinase like orphan receptor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 4920 | HGNC ID: HGNC:10257 | Ensembl Gene: ENSG00000169071 | OMIM ID: 602337 |
Expression of ROR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE20347 | ROR2 | 4920 | 205578_at | 0.2773 | 0.1082 | |
| GSE23400 | ROR2 | 4920 | 205578_at | 0.0692 | 0.1287 | |
| GSE29001 | ROR2 | 4920 | 205578_at | 0.4971 | 0.0708 | |
| GSE38129 | ROR2 | 4920 | 205578_at | 0.0762 | 0.8059 | |
| GSE53622 | ROR2 | 4920 | 13556 | -0.0089 | 0.9576 | |
| GSE53624 | ROR2 | 4920 | 13556 | 0.3738 | 0.0003 | |
| GSE97050 | ROR2 | 4920 | A_23_P158318 | -0.3597 | 0.2349 | |
| SRP007169 | ROR2 | 4920 | RNAseq | 2.2353 | 0.0003 | |
| SRP008496 | ROR2 | 4920 | RNAseq | 3.0709 | 0.0000 | |
| SRP064894 | ROR2 | 4920 | RNAseq | 0.3693 | 0.1670 | |
| SRP133303 | ROR2 | 4920 | RNAseq | 0.4141 | 0.2853 | |
| SRP159526 | ROR2 | 4920 | RNAseq | -0.0690 | 0.8689 | |
| SRP193095 | ROR2 | 4920 | RNAseq | 1.7213 | 0.0000 | |
| SRP219564 | ROR2 | 4920 | RNAseq | 0.3322 | 0.6112 | |
| TCGA | ROR2 | 4920 | RNAseq | -0.2879 | 0.0726 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ROR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ROR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ROR2 | 4920 | 6 | 9 | 15 | |
| GSE20123 | ROR2 | 4920 | 6 | 9 | 15 | |
| GSE43470 | ROR2 | 4920 | 6 | 4 | 33 | |
| GSE46452 | ROR2 | 4920 | 6 | 14 | 39 | |
| GSE47630 | ROR2 | 4920 | 1 | 18 | 21 | |
| GSE54993 | ROR2 | 4920 | 4 | 2 | 64 | |
| GSE54994 | ROR2 | 4920 | 8 | 11 | 34 | |
| GSE60625 | ROR2 | 4920 | 0 | 0 | 11 | |
| GSE74703 | ROR2 | 4920 | 5 | 3 | 28 | |
| GSE74704 | ROR2 | 4920 | 3 | 7 | 10 | |
| TCGA | ROR2 | 4920 | 22 | 24 | 50 |
Total number of gains: 67; Total number of losses: 101; Total Number of normals: 320.
Somatic mutations of ROR2:
Generating mutation plots.
Highly correlated genes for ROR2:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ROR2 | HSPB3 | 0.685599 | 3 | 0 | 3 |
| ROR2 | NACAD | 0.657275 | 4 | 0 | 3 |
| ROR2 | GPM6A | 0.645027 | 4 | 0 | 3 |
| ROR2 | NRK | 0.643682 | 3 | 0 | 3 |
| ROR2 | ZNF428 | 0.640496 | 5 | 0 | 3 |
| ROR2 | SLC4A3 | 0.630077 | 4 | 0 | 3 |
| ROR2 | PRAME | 0.62322 | 3 | 0 | 3 |
| ROR2 | ST8SIA1 | 0.619575 | 5 | 0 | 4 |
| ROR2 | PDLIM3 | 0.613195 | 3 | 0 | 3 |
| ROR2 | FHOD3 | 0.607849 | 3 | 0 | 3 |
| ROR2 | MICAL2 | 0.605671 | 7 | 0 | 4 |
| ROR2 | LY6H | 0.601366 | 3 | 0 | 3 |
| ROR2 | PLEKHO1 | 0.599792 | 5 | 0 | 4 |
| ROR2 | BIN1 | 0.596357 | 5 | 0 | 4 |
| ROR2 | GNAZ | 0.590793 | 5 | 0 | 3 |
| ROR2 | ULK2 | 0.590205 | 4 | 0 | 3 |
| ROR2 | SMARCA1 | 0.589314 | 6 | 0 | 4 |
| ROR2 | NID1 | 0.58652 | 6 | 0 | 5 |
| ROR2 | FLNA | 0.584829 | 6 | 0 | 5 |
| ROR2 | SAMD4A | 0.577021 | 4 | 0 | 3 |
For details and further investigation, click here
