| Full name: SERTA domain containing 3 | Alias Symbol: RBT1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 29946 | HGNC ID: HGNC:17931 | Ensembl Gene: ENSG00000167565 | OMIM ID: 612125 |
| Drug and gene relationship at DGIdb | |||
Expression of SERTAD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERTAD3 | 29946 | 219382_at | -0.2464 | 0.7018 | |
| GSE20347 | SERTAD3 | 29946 | 219382_at | -0.0783 | 0.5893 | |
| GSE23400 | SERTAD3 | 29946 | 219382_at | -0.0946 | 0.1519 | |
| GSE26886 | SERTAD3 | 29946 | 219382_at | -0.6432 | 0.0039 | |
| GSE29001 | SERTAD3 | 29946 | 219382_at | -0.3047 | 0.2537 | |
| GSE38129 | SERTAD3 | 29946 | 219382_at | -0.1168 | 0.6125 | |
| GSE45670 | SERTAD3 | 29946 | 219382_at | -0.1424 | 0.3580 | |
| GSE53622 | SERTAD3 | 29946 | 55582 | -0.3545 | 0.0002 | |
| GSE53624 | SERTAD3 | 29946 | 55582 | -0.1861 | 0.0028 | |
| GSE63941 | SERTAD3 | 29946 | 219382_at | -0.1092 | 0.8394 | |
| GSE77861 | SERTAD3 | 29946 | 219382_at | 0.3096 | 0.1483 | |
| GSE97050 | SERTAD3 | 29946 | A_23_P141960 | -0.7073 | 0.4107 | |
| SRP007169 | SERTAD3 | 29946 | RNAseq | -1.3395 | 0.0016 | |
| SRP008496 | SERTAD3 | 29946 | RNAseq | -0.9940 | 0.0000 | |
| SRP064894 | SERTAD3 | 29946 | RNAseq | 0.0976 | 0.6949 | |
| SRP133303 | SERTAD3 | 29946 | RNAseq | 0.0449 | 0.8332 | |
| SRP159526 | SERTAD3 | 29946 | RNAseq | -0.4486 | 0.0341 | |
| SRP193095 | SERTAD3 | 29946 | RNAseq | -0.2265 | 0.0692 | |
| SRP219564 | SERTAD3 | 29946 | RNAseq | -0.1539 | 0.7256 | |
| TCGA | SERTAD3 | 29946 | RNAseq | -0.0716 | 0.2583 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SERTAD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERTAD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERTAD3 | 29946 | 6 | 5 | 19 | |
| GSE20123 | SERTAD3 | 29946 | 6 | 4 | 20 | |
| GSE43470 | SERTAD3 | 29946 | 3 | 9 | 31 | |
| GSE46452 | SERTAD3 | 29946 | 48 | 1 | 10 | |
| GSE47630 | SERTAD3 | 29946 | 9 | 5 | 26 | |
| GSE54993 | SERTAD3 | 29946 | 17 | 4 | 49 | |
| GSE54994 | SERTAD3 | 29946 | 8 | 9 | 36 | |
| GSE60625 | SERTAD3 | 29946 | 9 | 0 | 2 | |
| GSE74703 | SERTAD3 | 29946 | 3 | 6 | 27 | |
| GSE74704 | SERTAD3 | 29946 | 6 | 2 | 12 | |
| TCGA | SERTAD3 | 29946 | 14 | 16 | 66 |
Total number of gains: 129; Total number of losses: 61; Total Number of normals: 298.
Somatic mutations of SERTAD3:
Generating mutation plots.
Highly correlated genes for SERTAD3:
Showing top 20/48 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERTAD3 | PTMS | 0.629332 | 3 | 0 | 3 |
| SERTAD3 | PIP5K1A | 0.62922 | 4 | 0 | 4 |
| SERTAD3 | CIC | 0.628371 | 4 | 0 | 4 |
| SERTAD3 | STXBP1 | 0.621993 | 3 | 0 | 3 |
| SERTAD3 | CSRNP1 | 0.617391 | 6 | 0 | 5 |
| SERTAD3 | SERTAD1 | 0.607364 | 7 | 0 | 7 |
| SERTAD3 | SMARCD3 | 0.605822 | 4 | 0 | 3 |
| SERTAD3 | RHBDF1 | 0.605276 | 3 | 0 | 3 |
| SERTAD3 | MAP4 | 0.603819 | 4 | 0 | 3 |
| SERTAD3 | SOX17 | 0.603354 | 4 | 0 | 3 |
| SERTAD3 | FOSB | 0.600235 | 9 | 0 | 8 |
| SERTAD3 | FABP3 | 0.593419 | 4 | 0 | 3 |
| SERTAD3 | IQGAP2 | 0.577955 | 3 | 0 | 3 |
| SERTAD3 | NR4A2 | 0.562669 | 7 | 0 | 4 |
| SERTAD3 | JUND | 0.558777 | 9 | 0 | 7 |
| SERTAD3 | RHOB | 0.55782 | 6 | 0 | 3 |
| SERTAD3 | SPTBN1 | 0.557344 | 3 | 0 | 3 |
| SERTAD3 | CBX4 | 0.557038 | 3 | 0 | 3 |
| SERTAD3 | ACTB | 0.556333 | 8 | 0 | 4 |
| SERTAD3 | SUPT5H | 0.553111 | 7 | 0 | 4 |
For details and further investigation, click here
