SPATA6L

 

Full name: spermatogenesis associated 6 like Alias Symbol: FLJ10058
Type: protein-coding gene Cytoband: 9p24.2-p24.1
Entrez ID: 55064 HGNC ID: HGNC:25472 Ensembl Gene: ENSG00000106686 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SPATA6L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SPATA6L 55064 1554708_s_at -0.5085 0.1230
GSE20347 SPATA6L 55064 220218_at -0.1455 0.0046
GSE23400 SPATA6L 55064 220218_at -0.2057 0.0000
GSE26886 SPATA6L 55064 1554708_s_at 0.0215 0.9171
GSE29001 SPATA6L 55064 220218_at -0.1670 0.2661
GSE38129 SPATA6L 55064 220218_at -0.2143 0.0000
GSE45670 SPATA6L 55064 1554708_s_at 0.0993 0.5656
GSE53622 SPATA6L 55064 16384 -0.0118 0.8704
GSE53624 SPATA6L 55064 16384 -0.1022 0.1543
GSE63941 SPATA6L 55064 1554708_s_at 0.5595 0.1772
GSE77861 SPATA6L 55064 1554708_s_at -0.0625 0.5710
SRP064894 SPATA6L 55064 RNAseq -0.4970 0.0561
SRP133303 SPATA6L 55064 RNAseq -0.0903 0.5616
SRP159526 SPATA6L 55064 RNAseq -1.0765 0.0117
SRP193095 SPATA6L 55064 RNAseq -0.4898 0.0037
SRP219564 SPATA6L 55064 RNAseq -0.8046 0.0494

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by SPATA6L expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of SPATA6L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SPATA6L 55064 1 17 12
GSE20123 SPATA6L 55064 1 16 13
GSE43470 SPATA6L 55064 4 11 28
GSE46452 SPATA6L 55064 2 23 34
GSE47630 SPATA6L 55064 5 26 9
GSE54993 SPATA6L 55064 6 3 61
GSE54994 SPATA6L 55064 9 17 27
GSE60625 SPATA6L 55064 0 2 9
GSE74703 SPATA6L 55064 4 8 24
GSE74704 SPATA6L 55064 0 12 8
TCGA SPATA6L 55064 14 50 32

Total number of gains: 46; Total number of losses: 185; Total Number of normals: 257.  


 

Somatic mutations of SPATA6L:

 

Generating mutation plots.

 

Highly correlated genes for SPATA6L:

 

Showing top 20/550 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SPATA6LGRIN10.669077303
SPATA6LGLYAT0.668794505
SPATA6LGPR170.668301303
SPATA6LCCIN0.664693606
SPATA6LCH25H0.653211303
SPATA6LACR0.652461303
SPATA6LPSG60.651855505
SPATA6LTTN0.650655404
SPATA6LGUCA1B0.645096606
SPATA6LPNLIPRP10.644627404
SPATA6LPAX30.640829403
SPATA6LSEZ6L0.640108404
SPATA6LCST80.638951403
SPATA6LCYP2A60.637551403
SPATA6LSPIN2A0.637492303
SPATA6LASIC20.636502504
SPATA6LASCL10.636313303
SPATA6LSIM20.636214404
SPATA6LACADVL0.635487404
SPATA6LCSN20.632953403

For details and further investigation, click here