| Full name: synapse differentiation inducing 1 | Alias Symbol: FLJ14220|IFITMD5|SynDIG1|DSPC2 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 79953 | HGNC ID: HGNC:15885 | Ensembl Gene: ENSG00000101463 | OMIM ID: 614311 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNDIG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNDIG1 | 79953 | 219310_at | 0.1288 | 0.8454 | |
| GSE20347 | SYNDIG1 | 79953 | 219310_at | 0.2628 | 0.0026 | |
| GSE23400 | SYNDIG1 | 79953 | 219310_at | -0.0268 | 0.4968 | |
| GSE26886 | SYNDIG1 | 79953 | 219310_at | 0.7435 | 0.0009 | |
| GSE29001 | SYNDIG1 | 79953 | 219310_at | -0.0012 | 0.9957 | |
| GSE38129 | SYNDIG1 | 79953 | 219310_at | 0.2740 | 0.0374 | |
| GSE45670 | SYNDIG1 | 79953 | 219310_at | -0.0702 | 0.7696 | |
| GSE53622 | SYNDIG1 | 79953 | 57929 | 1.5121 | 0.0000 | |
| GSE53624 | SYNDIG1 | 79953 | 57929 | 1.8936 | 0.0000 | |
| GSE63941 | SYNDIG1 | 79953 | 219310_at | 0.2584 | 0.5460 | |
| GSE77861 | SYNDIG1 | 79953 | 219310_at | 0.0474 | 0.7018 | |
| GSE97050 | SYNDIG1 | 79953 | A_23_P251043 | 0.1000 | 0.6375 | |
| SRP007169 | SYNDIG1 | 79953 | RNAseq | 3.4735 | 0.0010 | |
| SRP133303 | SYNDIG1 | 79953 | RNAseq | 2.4979 | 0.0000 | |
| SRP219564 | SYNDIG1 | 79953 | RNAseq | 3.1650 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SYNDIG1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SYNDIG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNDIG1 | 79953 | 12 | 2 | 16 | |
| GSE20123 | SYNDIG1 | 79953 | 12 | 2 | 16 | |
| GSE43470 | SYNDIG1 | 79953 | 12 | 1 | 30 | |
| GSE46452 | SYNDIG1 | 79953 | 27 | 1 | 31 | |
| GSE47630 | SYNDIG1 | 79953 | 17 | 4 | 19 | |
| GSE54993 | SYNDIG1 | 79953 | 0 | 17 | 53 | |
| GSE54994 | SYNDIG1 | 79953 | 27 | 1 | 25 | |
| GSE60625 | SYNDIG1 | 79953 | 0 | 0 | 11 | |
| GSE74703 | SYNDIG1 | 79953 | 10 | 1 | 25 | |
| GSE74704 | SYNDIG1 | 79953 | 7 | 1 | 12 | |
| TCGA | SYNDIG1 | 79953 | 43 | 10 | 43 |
Total number of gains: 167; Total number of losses: 40; Total Number of normals: 281.
Somatic mutations of SYNDIG1:
Generating mutation plots.
Highly correlated genes for SYNDIG1:
Showing top 20/422 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNDIG1 | CTHRC1 | 0.7426 | 4 | 0 | 4 |
| SYNDIG1 | SHISA2 | 0.699082 | 4 | 0 | 4 |
| SYNDIG1 | THY1 | 0.693648 | 6 | 0 | 6 |
| SYNDIG1 | LBX2-AS1 | 0.685102 | 4 | 0 | 4 |
| SYNDIG1 | POSTN | 0.678549 | 6 | 0 | 6 |
| SYNDIG1 | NAT14 | 0.668045 | 3 | 0 | 3 |
| SYNDIG1 | COL5A1 | 0.666591 | 7 | 0 | 6 |
| SYNDIG1 | LOXL3 | 0.662198 | 4 | 0 | 4 |
| SYNDIG1 | TRAM2 | 0.66176 | 5 | 0 | 5 |
| SYNDIG1 | COL5A2 | 0.659946 | 7 | 0 | 6 |
| SYNDIG1 | FNDC1 | 0.655265 | 5 | 0 | 5 |
| SYNDIG1 | MFAP2 | 0.654529 | 6 | 0 | 6 |
| SYNDIG1 | OLFML2B | 0.651327 | 6 | 0 | 5 |
| SYNDIG1 | COL10A1 | 0.64447 | 6 | 0 | 6 |
| SYNDIG1 | CTSK | 0.640266 | 7 | 0 | 5 |
| SYNDIG1 | DENND5B | 0.637815 | 3 | 0 | 3 |
| SYNDIG1 | CMTM3 | 0.636767 | 5 | 0 | 4 |
| SYNDIG1 | SPARC | 0.633894 | 6 | 0 | 6 |
| SYNDIG1 | IKBIP | 0.633234 | 3 | 0 | 3 |
| SYNDIG1 | COL6A3 | 0.63239 | 7 | 0 | 6 |
For details and further investigation, click here
