| Full name: ubiquitin like modifier activating enzyme 7 | Alias Symbol: D8|UBE2|UBA1B | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 7318 | HGNC ID: HGNC:12471 | Ensembl Gene: ENSG00000182179 | OMIM ID: 191325 |
| Drug and gene relationship at DGIdb | |||
Expression of UBA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | UBA7 | 7318 | 8615 | -0.4861 | 0.0000 | |
| GSE53624 | UBA7 | 7318 | 8615 | -0.4398 | 0.0000 | |
| GSE97050 | UBA7 | 7318 | A_23_P21207 | 0.1896 | 0.5095 | |
| SRP007169 | UBA7 | 7318 | RNAseq | -1.1366 | 0.0418 | |
| SRP008496 | UBA7 | 7318 | RNAseq | -1.1729 | 0.0018 | |
| SRP064894 | UBA7 | 7318 | RNAseq | -0.0099 | 0.9604 | |
| SRP133303 | UBA7 | 7318 | RNAseq | -0.8215 | 0.0004 | |
| SRP159526 | UBA7 | 7318 | RNAseq | -1.2042 | 0.0028 | |
| SRP193095 | UBA7 | 7318 | RNAseq | -0.4309 | 0.0472 | |
| SRP219564 | UBA7 | 7318 | RNAseq | -0.0615 | 0.7876 | |
| TCGA | UBA7 | 7318 | RNAseq | -0.3145 | 0.0041 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by UBA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBA7 | 7318 | 0 | 18 | 12 | |
| GSE20123 | UBA7 | 7318 | 0 | 19 | 11 | |
| GSE43470 | UBA7 | 7318 | 0 | 18 | 25 | |
| GSE46452 | UBA7 | 7318 | 2 | 16 | 41 | |
| GSE47630 | UBA7 | 7318 | 1 | 24 | 15 | |
| GSE54993 | UBA7 | 7318 | 6 | 2 | 62 | |
| GSE54994 | UBA7 | 7318 | 0 | 35 | 18 | |
| GSE60625 | UBA7 | 7318 | 5 | 0 | 6 | |
| GSE74703 | UBA7 | 7318 | 0 | 14 | 22 | |
| GSE74704 | UBA7 | 7318 | 0 | 12 | 8 | |
| TCGA | UBA7 | 7318 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of UBA7:
Generating mutation plots.
Highly correlated genes for UBA7:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBA7 | ACSL5 | 0.702218 | 4 | 0 | 4 |
| UBA7 | HLA-DMA | 0.699235 | 4 | 0 | 4 |
| UBA7 | VAMP5 | 0.697123 | 3 | 0 | 3 |
| UBA7 | CD74 | 0.696289 | 4 | 0 | 3 |
| UBA7 | CD3E | 0.693097 | 3 | 0 | 3 |
| UBA7 | PARP15 | 0.689337 | 3 | 0 | 3 |
| UBA7 | GRAP2 | 0.688228 | 3 | 0 | 3 |
| UBA7 | GNGT2 | 0.68256 | 3 | 0 | 3 |
| UBA7 | GIMAP6 | 0.682197 | 3 | 0 | 3 |
| UBA7 | GIMAP7 | 0.681629 | 4 | 0 | 4 |
| UBA7 | GPR171 | 0.680534 | 3 | 0 | 3 |
| UBA7 | SAMD9L | 0.677109 | 4 | 0 | 4 |
| UBA7 | IKZF3 | 0.671615 | 3 | 0 | 3 |
| UBA7 | GIMAP1 | 0.669484 | 3 | 0 | 3 |
| UBA7 | ACAP1 | 0.663743 | 4 | 0 | 3 |
| UBA7 | IL2RG | 0.659634 | 3 | 0 | 3 |
| UBA7 | CD2 | 0.65796 | 4 | 0 | 3 |
| UBA7 | PIK3R6 | 0.65527 | 3 | 0 | 3 |
| UBA7 | TRIM22 | 0.65521 | 4 | 0 | 3 |
| UBA7 | IL15 | 0.654628 | 3 | 0 | 3 |
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