| Full name: WD repeat domain 76 | Alias Symbol: FLJ12973 | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 79968 | HGNC ID: HGNC:25773 | Ensembl Gene: ENSG00000092470 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR76:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR76 | 79968 | 205519_at | 0.6181 | 0.3380 | |
| GSE20347 | WDR76 | 79968 | 205519_at | 0.2276 | 0.0351 | |
| GSE23400 | WDR76 | 79968 | 205519_at | 0.1505 | 0.0001 | |
| GSE26886 | WDR76 | 79968 | 205519_at | 0.4952 | 0.0039 | |
| GSE29001 | WDR76 | 79968 | 205519_at | 0.1875 | 0.0966 | |
| GSE38129 | WDR76 | 79968 | 205519_at | 0.3797 | 0.0001 | |
| GSE45670 | WDR76 | 79968 | 205519_at | 0.2988 | 0.1557 | |
| GSE53622 | WDR76 | 79968 | 9478 | 0.7881 | 0.0000 | |
| GSE53624 | WDR76 | 79968 | 9478 | 0.8661 | 0.0000 | |
| GSE63941 | WDR76 | 79968 | 205519_at | 1.5989 | 0.0550 | |
| GSE77861 | WDR76 | 79968 | 205519_at | 0.0602 | 0.6054 | |
| SRP007169 | WDR76 | 79968 | RNAseq | 1.6850 | 0.0047 | |
| SRP064894 | WDR76 | 79968 | RNAseq | 0.9219 | 0.0001 | |
| SRP133303 | WDR76 | 79968 | RNAseq | 1.0454 | 0.0000 | |
| SRP159526 | WDR76 | 79968 | RNAseq | 0.6882 | 0.0510 | |
| SRP193095 | WDR76 | 79968 | RNAseq | 0.6738 | 0.0000 | |
| SRP219564 | WDR76 | 79968 | RNAseq | 0.7613 | 0.0550 | |
| TCGA | WDR76 | 79968 | RNAseq | 0.5603 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by WDR76 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR76:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR76 | 79968 | 3 | 4 | 23 | |
| GSE20123 | WDR76 | 79968 | 3 | 5 | 22 | |
| GSE43470 | WDR76 | 79968 | 3 | 4 | 36 | |
| GSE46452 | WDR76 | 79968 | 3 | 7 | 49 | |
| GSE47630 | WDR76 | 79968 | 8 | 10 | 22 | |
| GSE54993 | WDR76 | 79968 | 4 | 6 | 60 | |
| GSE54994 | WDR76 | 79968 | 5 | 7 | 41 | |
| GSE60625 | WDR76 | 79968 | 4 | 0 | 7 | |
| GSE74703 | WDR76 | 79968 | 3 | 3 | 30 | |
| GSE74704 | WDR76 | 79968 | 2 | 2 | 16 | |
| TCGA | WDR76 | 79968 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 65; Total Number of normals: 373.
Somatic mutations of WDR76:
Generating mutation plots.
Highly correlated genes for WDR76:
Showing top 20/509 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR76 | ARL6IP6 | 0.659055 | 5 | 0 | 5 |
| WDR76 | BORA | 0.652464 | 5 | 0 | 5 |
| WDR76 | CASP6 | 0.647815 | 4 | 0 | 3 |
| WDR76 | TIPIN | 0.646852 | 10 | 0 | 8 |
| WDR76 | OIP5 | 0.643546 | 7 | 0 | 6 |
| WDR76 | CEP78 | 0.64296 | 6 | 0 | 6 |
| WDR76 | ORC1 | 0.639489 | 9 | 0 | 8 |
| WDR76 | UBL7-AS1 | 0.637026 | 5 | 0 | 4 |
| WDR76 | RAD51 | 0.634431 | 10 | 0 | 7 |
| WDR76 | DDX20 | 0.63231 | 4 | 0 | 3 |
| WDR76 | CPSF3 | 0.630045 | 5 | 0 | 5 |
| WDR76 | FEN1 | 0.623128 | 8 | 0 | 7 |
| WDR76 | PSRC1 | 0.621232 | 9 | 0 | 8 |
| WDR76 | ARHGAP11A | 0.620635 | 8 | 0 | 7 |
| WDR76 | MSH2 | 0.619997 | 8 | 0 | 6 |
| WDR76 | KNSTRN | 0.61982 | 6 | 0 | 5 |
| WDR76 | SKA3 | 0.61968 | 4 | 0 | 4 |
| WDR76 | POLE4 | 0.619279 | 6 | 0 | 6 |
| WDR76 | PHF19 | 0.615316 | 6 | 0 | 4 |
| WDR76 | NIFK | 0.614591 | 4 | 0 | 3 |
For details and further investigation, click here
