| Full name: centromere protein P | Alias Symbol: RP11-19J3.3|CENP-P | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 401541 | HGNC ID: HGNC:32933 | Ensembl Gene: ENSG00000188312 | OMIM ID: 611505 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CENPP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CENPP | 401541 | 8681 | 0.7678 | 0.0000 | |
| GSE53624 | CENPP | 401541 | 8681 | 0.8493 | 0.0000 | |
| GSE97050 | CENPP | 401541 | A_33_P3387931 | 0.1153 | 0.6727 | |
| SRP007169 | CENPP | 401541 | RNAseq | 1.4490 | 0.0967 | |
| SRP008496 | CENPP | 401541 | RNAseq | 0.7460 | 0.4058 | |
| SRP064894 | CENPP | 401541 | RNAseq | 0.6380 | 0.0087 | |
| SRP133303 | CENPP | 401541 | RNAseq | 0.7985 | 0.0002 | |
| SRP159526 | CENPP | 401541 | RNAseq | 0.6333 | 0.0979 | |
| SRP193095 | CENPP | 401541 | RNAseq | 0.4441 | 0.0464 | |
| SRP219564 | CENPP | 401541 | RNAseq | 0.4521 | 0.1647 | |
| TCGA | CENPP | 401541 | RNAseq | 0.8090 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CENPP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPP | 401541 | 6 | 9 | 15 | |
| GSE20123 | CENPP | 401541 | 6 | 9 | 15 | |
| GSE43470 | CENPP | 401541 | 6 | 4 | 33 | |
| GSE46452 | CENPP | 401541 | 6 | 14 | 39 | |
| GSE47630 | CENPP | 401541 | 1 | 17 | 22 | |
| GSE54993 | CENPP | 401541 | 4 | 2 | 64 | |
| GSE54994 | CENPP | 401541 | 8 | 11 | 34 | |
| GSE60625 | CENPP | 401541 | 0 | 0 | 11 | |
| GSE74703 | CENPP | 401541 | 5 | 3 | 28 | |
| GSE74704 | CENPP | 401541 | 3 | 7 | 10 | |
| TCGA | CENPP | 401541 | 24 | 24 | 48 |
Total number of gains: 69; Total number of losses: 100; Total Number of normals: 319.
Somatic mutations of CENPP:
Generating mutation plots.
Highly correlated genes for CENPP:
Showing top 20/27 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPP | SLC3A2 | 0.662905 | 3 | 0 | 3 |
| CENPP | EGFL6 | 0.652127 | 3 | 0 | 3 |
| CENPP | FOXE1 | 0.615538 | 3 | 0 | 3 |
| CENPP | PSME3 | 0.607806 | 3 | 0 | 3 |
| CENPP | GPC1 | 0.597942 | 3 | 0 | 3 |
| CENPP | BRIX1 | 0.587147 | 3 | 0 | 3 |
| CENPP | XPOT | 0.580662 | 3 | 0 | 3 |
| CENPP | ORC1 | 0.573927 | 3 | 0 | 3 |
| CENPP | MRPL13 | 0.561224 | 3 | 0 | 3 |
| CENPP | SLC44A1 | 0.560019 | 4 | 0 | 3 |
| CENPP | KIF18A | 0.556262 | 3 | 0 | 3 |
| CENPP | CKS2 | 0.554335 | 4 | 0 | 3 |
| CENPP | ZNF469 | 0.553341 | 3 | 0 | 3 |
| CENPP | POLE3 | 0.552676 | 4 | 0 | 3 |
| CENPP | ESCO2 | 0.548448 | 3 | 0 | 3 |
| CENPP | KIF15 | 0.548269 | 3 | 0 | 3 |
| CENPP | DCAF13 | 0.546248 | 3 | 0 | 3 |
| CENPP | PTK7 | 0.545652 | 3 | 0 | 3 |
| CENPP | CDCA3 | 0.540824 | 3 | 0 | 3 |
| CENPP | LAMB3 | 0.539178 | 3 | 0 | 3 |
For details and further investigation, click here
