| Full name: Fas apoptotic inhibitory molecule | Alias Symbol: FLJ10582|FAIM1 | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 55179 | HGNC ID: HGNC:18703 | Ensembl Gene: ENSG00000158234 | OMIM ID: 617535 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAIM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAIM | 55179 | 220643_s_at | 0.4615 | 0.3911 | |
| GSE20347 | FAIM | 55179 | 220643_s_at | 0.5332 | 0.0037 | |
| GSE23400 | FAIM | 55179 | 220643_s_at | 0.4008 | 0.0000 | |
| GSE26886 | FAIM | 55179 | 220643_s_at | -0.0390 | 0.9260 | |
| GSE29001 | FAIM | 55179 | 220643_s_at | 0.6867 | 0.1489 | |
| GSE38129 | FAIM | 55179 | 220643_s_at | 0.5977 | 0.0001 | |
| GSE45670 | FAIM | 55179 | 220643_s_at | 0.3618 | 0.0533 | |
| GSE53622 | FAIM | 55179 | 58228 | 0.3213 | 0.0003 | |
| GSE53624 | FAIM | 55179 | 58228 | 0.1784 | 0.0270 | |
| GSE63941 | FAIM | 55179 | 220643_s_at | 0.7231 | 0.2132 | |
| GSE77861 | FAIM | 55179 | 220643_s_at | -0.1047 | 0.7953 | |
| GSE97050 | FAIM | 55179 | A_23_P253932 | 0.4634 | 0.1859 | |
| SRP007169 | FAIM | 55179 | RNAseq | 0.0635 | 0.8727 | |
| SRP008496 | FAIM | 55179 | RNAseq | 0.4122 | 0.2188 | |
| SRP064894 | FAIM | 55179 | RNAseq | 0.5122 | 0.0226 | |
| SRP133303 | FAIM | 55179 | RNAseq | 0.5814 | 0.0046 | |
| SRP159526 | FAIM | 55179 | RNAseq | 0.5016 | 0.2189 | |
| SRP193095 | FAIM | 55179 | RNAseq | 0.3076 | 0.1251 | |
| SRP219564 | FAIM | 55179 | RNAseq | 0.3384 | 0.3362 | |
| TCGA | FAIM | 55179 | RNAseq | 0.2865 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAIM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAIM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAIM | 55179 | 17 | 0 | 13 | |
| GSE20123 | FAIM | 55179 | 17 | 0 | 13 | |
| GSE43470 | FAIM | 55179 | 22 | 0 | 21 | |
| GSE46452 | FAIM | 55179 | 15 | 4 | 40 | |
| GSE47630 | FAIM | 55179 | 18 | 3 | 19 | |
| GSE54993 | FAIM | 55179 | 2 | 8 | 60 | |
| GSE54994 | FAIM | 55179 | 32 | 1 | 20 | |
| GSE60625 | FAIM | 55179 | 0 | 6 | 5 | |
| GSE74703 | FAIM | 55179 | 19 | 0 | 17 | |
| GSE74704 | FAIM | 55179 | 11 | 0 | 9 | |
| TCGA | FAIM | 55179 | 62 | 4 | 30 |
Total number of gains: 215; Total number of losses: 26; Total Number of normals: 247.
Somatic mutations of FAIM:
Generating mutation plots.
Highly correlated genes for FAIM:
Showing top 20/181 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAIM | PODXL | 0.63747 | 3 | 0 | 3 |
| FAIM | TOPBP1 | 0.632309 | 7 | 0 | 6 |
| FAIM | FZD6 | 0.629532 | 7 | 0 | 6 |
| FAIM | SHQ1 | 0.617936 | 3 | 0 | 3 |
| FAIM | MRPL3 | 0.605138 | 10 | 0 | 8 |
| FAIM | MMP10 | 0.596486 | 3 | 0 | 3 |
| FAIM | HMCES | 0.594197 | 8 | 0 | 8 |
| FAIM | EIF2AK1 | 0.589893 | 5 | 0 | 5 |
| FAIM | EXO1 | 0.587793 | 7 | 0 | 5 |
| FAIM | TTC30A | 0.586724 | 5 | 0 | 3 |
| FAIM | COPB2 | 0.585665 | 9 | 0 | 8 |
| FAIM | SLC33A1 | 0.584925 | 8 | 0 | 7 |
| FAIM | C17orf75 | 0.583742 | 7 | 0 | 6 |
| FAIM | HYLS1 | 0.580042 | 5 | 0 | 3 |
| FAIM | ATAD3B | 0.576367 | 3 | 0 | 3 |
| FAIM | PIK3R4 | 0.575716 | 11 | 0 | 8 |
| FAIM | RYK | 0.575598 | 8 | 0 | 5 |
| FAIM | ECT2 | 0.575276 | 9 | 0 | 6 |
| FAIM | SPCS2 | 0.572792 | 5 | 0 | 3 |
| FAIM | RNF7 | 0.568679 | 9 | 0 | 6 |
For details and further investigation, click here
