| Full name: fibroblast growth factor binding protein 1 | Alias Symbol: HBP17|FGFBP | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 9982 | HGNC ID: HGNC:19695 | Ensembl Gene: ENSG00000137440 | OMIM ID: 607737 |
| Drug and gene relationship at DGIdb | |||
Expression of FGFBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGFBP1 | 9982 | 205014_at | -1.0331 | 0.6752 | |
| GSE20347 | FGFBP1 | 9982 | 205014_at | -1.7525 | 0.0002 | |
| GSE23400 | FGFBP1 | 9982 | 205014_at | -0.7588 | 0.0017 | |
| GSE26886 | FGFBP1 | 9982 | 205014_at | -1.9416 | 0.0076 | |
| GSE29001 | FGFBP1 | 9982 | 205014_at | -1.3921 | 0.0668 | |
| GSE38129 | FGFBP1 | 9982 | 205014_at | -0.6941 | 0.2944 | |
| GSE45670 | FGFBP1 | 9982 | 205014_at | -0.3723 | 0.3431 | |
| GSE53622 | FGFBP1 | 9982 | 49072 | -1.3380 | 0.0005 | |
| GSE53624 | FGFBP1 | 9982 | 49072 | -1.2784 | 0.0000 | |
| GSE63941 | FGFBP1 | 9982 | 205014_at | 3.7818 | 0.0325 | |
| GSE77861 | FGFBP1 | 9982 | 205014_at | -0.6219 | 0.2745 | |
| GSE97050 | FGFBP1 | 9982 | A_23_P30126 | 0.5293 | 0.8080 | |
| SRP007169 | FGFBP1 | 9982 | RNAseq | -0.1469 | 0.8687 | |
| SRP008496 | FGFBP1 | 9982 | RNAseq | -0.6721 | 0.5046 | |
| SRP064894 | FGFBP1 | 9982 | RNAseq | -1.7002 | 0.0008 | |
| SRP133303 | FGFBP1 | 9982 | RNAseq | -1.4028 | 0.0022 | |
| SRP159526 | FGFBP1 | 9982 | RNAseq | -1.5549 | 0.0381 | |
| SRP193095 | FGFBP1 | 9982 | RNAseq | -0.6468 | 0.1723 | |
| SRP219564 | FGFBP1 | 9982 | RNAseq | -1.1622 | 0.3635 | |
| TCGA | FGFBP1 | 9982 | RNAseq | 1.1740 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 7.
Survival by FGFBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGFBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGFBP1 | 9982 | 1 | 17 | 12 | |
| GSE20123 | FGFBP1 | 9982 | 1 | 17 | 12 | |
| GSE43470 | FGFBP1 | 9982 | 1 | 15 | 27 | |
| GSE46452 | FGFBP1 | 9982 | 1 | 36 | 22 | |
| GSE47630 | FGFBP1 | 9982 | 1 | 19 | 20 | |
| GSE54993 | FGFBP1 | 9982 | 10 | 0 | 60 | |
| GSE54994 | FGFBP1 | 9982 | 4 | 12 | 37 | |
| GSE60625 | FGFBP1 | 9982 | 0 | 0 | 11 | |
| GSE74703 | FGFBP1 | 9982 | 1 | 13 | 22 | |
| GSE74704 | FGFBP1 | 9982 | 1 | 10 | 9 | |
| TCGA | FGFBP1 | 9982 | 9 | 47 | 40 |
Total number of gains: 30; Total number of losses: 186; Total Number of normals: 272.
Somatic mutations of FGFBP1:
Generating mutation plots.
Highly correlated genes for FGFBP1:
Showing top 20/557 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGFBP1 | ARAP2 | 0.742517 | 3 | 0 | 3 |
| FGFBP1 | KRT6C | 0.717302 | 4 | 0 | 3 |
| FGFBP1 | DPH6 | 0.701906 | 3 | 0 | 3 |
| FGFBP1 | SERPINB5 | 0.701107 | 13 | 0 | 12 |
| FGFBP1 | GJB5 | 0.699397 | 10 | 0 | 9 |
| FGFBP1 | SERPINB2 | 0.68608 | 12 | 0 | 11 |
| FGFBP1 | KRT83 | 0.675036 | 4 | 0 | 3 |
| FGFBP1 | TMEM154 | 0.670912 | 8 | 0 | 6 |
| FGFBP1 | SPRR1B | 0.666268 | 11 | 0 | 9 |
| FGFBP1 | LPAR5 | 0.664356 | 8 | 0 | 6 |
| FGFBP1 | MALL | 0.652452 | 12 | 0 | 10 |
| FGFBP1 | DSG3 | 0.649183 | 13 | 0 | 10 |
| FGFBP1 | RAB38 | 0.647575 | 12 | 0 | 10 |
| FGFBP1 | PKP3 | 0.646845 | 13 | 0 | 11 |
| FGFBP1 | KRT5 | 0.645901 | 7 | 0 | 5 |
| FGFBP1 | S100A16 | 0.644844 | 8 | 0 | 7 |
| FGFBP1 | KLF5 | 0.644323 | 11 | 0 | 9 |
| FGFBP1 | CERS3 | 0.642869 | 6 | 0 | 4 |
| FGFBP1 | DENND2C | 0.641963 | 8 | 0 | 7 |
| FGFBP1 | FAM160A1 | 0.641341 | 6 | 0 | 6 |
For details and further investigation, click here
