| Full name: ubiquitin conjugating enzyme E2 Z | Alias Symbol: FLJ13855|USE1 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 65264 | HGNC ID: HGNC:25847 | Ensembl Gene: ENSG00000159202 | OMIM ID: 611362 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2Z:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2Z | 65264 | 217750_s_at | 0.2849 | 0.3750 | |
| GSE20347 | UBE2Z | 65264 | 217750_s_at | 0.3549 | 0.0046 | |
| GSE23400 | UBE2Z | 65264 | 217750_s_at | 0.4522 | 0.0000 | |
| GSE26886 | UBE2Z | 65264 | 217750_s_at | -0.3605 | 0.0540 | |
| GSE29001 | UBE2Z | 65264 | 217750_s_at | 0.2323 | 0.2256 | |
| GSE38129 | UBE2Z | 65264 | 217750_s_at | 0.4722 | 0.0000 | |
| GSE45670 | UBE2Z | 65264 | 217750_s_at | 0.3281 | 0.0186 | |
| GSE53622 | UBE2Z | 65264 | 53281 | 0.3735 | 0.0000 | |
| GSE53624 | UBE2Z | 65264 | 8858 | 0.6391 | 0.0000 | |
| GSE63941 | UBE2Z | 65264 | 217750_s_at | 0.1474 | 0.6812 | |
| GSE77861 | UBE2Z | 65264 | 217750_s_at | 0.4501 | 0.0249 | |
| GSE97050 | UBE2Z | 65264 | A_33_P3390521 | 0.4584 | 0.1506 | |
| SRP007169 | UBE2Z | 65264 | RNAseq | 0.4641 | 0.1470 | |
| SRP008496 | UBE2Z | 65264 | RNAseq | 0.2366 | 0.1994 | |
| SRP064894 | UBE2Z | 65264 | RNAseq | 0.7170 | 0.0000 | |
| SRP133303 | UBE2Z | 65264 | RNAseq | 0.4895 | 0.0026 | |
| SRP159526 | UBE2Z | 65264 | RNAseq | 0.4806 | 0.0005 | |
| SRP193095 | UBE2Z | 65264 | RNAseq | 0.3777 | 0.0000 | |
| SRP219564 | UBE2Z | 65264 | RNAseq | 0.4532 | 0.0735 | |
| TCGA | UBE2Z | 65264 | RNAseq | 0.0869 | 0.0476 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBE2Z expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2Z:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2Z | 65264 | 6 | 2 | 22 | |
| GSE20123 | UBE2Z | 65264 | 6 | 2 | 22 | |
| GSE43470 | UBE2Z | 65264 | 3 | 1 | 39 | |
| GSE46452 | UBE2Z | 65264 | 32 | 0 | 27 | |
| GSE47630 | UBE2Z | 65264 | 9 | 0 | 31 | |
| GSE54993 | UBE2Z | 65264 | 2 | 4 | 64 | |
| GSE54994 | UBE2Z | 65264 | 10 | 6 | 37 | |
| GSE60625 | UBE2Z | 65264 | 4 | 0 | 7 | |
| GSE74703 | UBE2Z | 65264 | 3 | 1 | 32 | |
| GSE74704 | UBE2Z | 65264 | 4 | 1 | 15 | |
| TCGA | UBE2Z | 65264 | 26 | 7 | 63 |
Total number of gains: 105; Total number of losses: 24; Total Number of normals: 359.
Somatic mutations of UBE2Z:
Generating mutation plots.
Highly correlated genes for UBE2Z:
Showing top 20/897 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2Z | CXCL5 | 0.782061 | 3 | 0 | 3 |
| UBE2Z | NIPA1 | 0.778677 | 4 | 0 | 4 |
| UBE2Z | CD53 | 0.741547 | 3 | 0 | 3 |
| UBE2Z | UBE3C | 0.735669 | 5 | 0 | 4 |
| UBE2Z | SPOP | 0.720866 | 3 | 0 | 3 |
| UBE2Z | KDM4A | 0.714937 | 3 | 0 | 3 |
| UBE2Z | SPRR2G | 0.713075 | 3 | 0 | 3 |
| UBE2Z | ALPK2 | 0.712898 | 3 | 0 | 3 |
| UBE2Z | SMAP2 | 0.711865 | 3 | 0 | 3 |
| UBE2Z | SFT2D3 | 0.709914 | 3 | 0 | 3 |
| UBE2Z | FXR1 | 0.700448 | 6 | 0 | 6 |
| UBE2Z | ALG10 | 0.698845 | 4 | 0 | 3 |
| UBE2Z | KLF11 | 0.698409 | 3 | 0 | 3 |
| UBE2Z | CSF1R | 0.695277 | 3 | 0 | 3 |
| UBE2Z | ATP6V1B2 | 0.68496 | 4 | 0 | 4 |
| UBE2Z | UNC5B | 0.679352 | 3 | 0 | 3 |
| UBE2Z | TCF7L1 | 0.677383 | 3 | 0 | 3 |
| UBE2Z | LTB | 0.676441 | 3 | 0 | 3 |
| UBE2Z | BCL7B | 0.676281 | 3 | 0 | 3 |
| UBE2Z | POLRMT | 0.675229 | 3 | 0 | 3 |
For details and further investigation, click here
