| Full name: zona pellucida glycoprotein 3 | Alias Symbol: ZP3-424|ZP3-372|ZPC | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 7784 | HGNC ID: HGNC:13189 | Ensembl Gene: ENSG00000188372 | OMIM ID: 182889 |
Expression of ZP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ZP3 | 7784 | 49888 | 0.7253 | 0.0000 | |
| GSE53624 | ZP3 | 7784 | 49888 | 0.9211 | 0.0000 | |
| GSE97050 | ZP3 | 7784 | A_23_P134419 | 0.5234 | 0.2385 | |
| SRP064894 | ZP3 | 7784 | RNAseq | 1.1018 | 0.0026 | |
| SRP133303 | ZP3 | 7784 | RNAseq | 0.8547 | 0.0159 | |
| SRP159526 | ZP3 | 7784 | RNAseq | 0.9698 | 0.0132 | |
| SRP219564 | ZP3 | 7784 | RNAseq | 1.2686 | 0.0807 | |
| TCGA | ZP3 | 7784 | RNAseq | 0.8945 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZP3 | 7784 | 15 | 1 | 14 | |
| GSE20123 | ZP3 | 7784 | 15 | 1 | 14 | |
| GSE43470 | ZP3 | 7784 | 3 | 2 | 38 | |
| GSE46452 | ZP3 | 7784 | 11 | 0 | 48 | |
| GSE47630 | ZP3 | 7784 | 7 | 3 | 30 | |
| GSE54993 | ZP3 | 7784 | 2 | 7 | 61 | |
| GSE54994 | ZP3 | 7784 | 14 | 3 | 36 | |
| GSE60625 | ZP3 | 7784 | 0 | 0 | 11 | |
| GSE74703 | ZP3 | 7784 | 3 | 1 | 32 | |
| GSE74704 | ZP3 | 7784 | 8 | 1 | 11 | |
| TCGA | ZP3 | 7784 | 44 | 5 | 47 |
Total number of gains: 122; Total number of losses: 24; Total Number of normals: 342.
Somatic mutations of ZP3:
Generating mutation plots.
Highly correlated genes for ZP3:
Showing top 20/27 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZP3 | ASF1B | 0.720654 | 3 | 0 | 3 |
| ZP3 | POC1A | 0.695616 | 3 | 0 | 3 |
| ZP3 | CDCA8 | 0.68986 | 3 | 0 | 3 |
| ZP3 | FLAD1 | 0.689642 | 3 | 0 | 3 |
| ZP3 | CDC20 | 0.683129 | 3 | 0 | 3 |
| ZP3 | RAD51 | 0.675904 | 4 | 0 | 4 |
| ZP3 | CDCA5 | 0.655388 | 3 | 0 | 3 |
| ZP3 | WDR74 | 0.650715 | 4 | 0 | 4 |
| ZP3 | DEPDC1B | 0.647153 | 3 | 0 | 3 |
| ZP3 | PYCR1 | 0.645965 | 3 | 0 | 3 |
| ZP3 | EXO1 | 0.645684 | 3 | 0 | 3 |
| ZP3 | IRAK1 | 0.640292 | 3 | 0 | 3 |
| ZP3 | MCM7 | 0.626975 | 3 | 0 | 3 |
| ZP3 | PDCD11 | 0.619158 | 3 | 0 | 3 |
| ZP3 | CPSF4 | 0.615805 | 4 | 0 | 4 |
| ZP3 | ECE2 | 0.614383 | 3 | 0 | 3 |
| ZP3 | CDC25C | 0.610361 | 3 | 0 | 3 |
| ZP3 | RAD54B | 0.602511 | 3 | 0 | 3 |
| ZP3 | BOP1 | 0.599823 | 4 | 0 | 3 |
| ZP3 | PUS7 | 0.59657 | 3 | 0 | 3 |
For details and further investigation, click here
